Evidence map›Paper›PMID 42653393›Full record

ReviewInternational journal of molecular sciences2026

Obstacles and Trials in Treating Primary Brain Tumors.

Stefana Oana Popescu, Delia Codruta Popa, Oana Alexandru, Anica Dricu

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Stefana Oana PopescuDepartment of Biochemistry, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Petru Rares Street No. 2-4, 200349 Craiova, Romania.
Delia Codruta PopaDepartment of Hematology, Fundeni Clinical Institute, Soseaua Fundeni No. 258, 022328 Bucharest, Romania.ORCID 0000-0002-7638-3285
Oana AlexandruDepartment of Neurology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Petru Rares Street No. 2-4, 200349 Craiova, Romania.ORCID 0000-0003-3868-5378
Anica DricuDepartment of Biochemistry, Faculty of Medicine, "Carol Davila" University of Medicine and Pharmacy, Bd Eroii Sanitari 8, 050474 Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Brain tumor (BT) patients can experience neurological complications as a result of the disease itself or after exposure to anticancer treatment. It is already known that BT patients have a poor survival and quality of life due to tumor progression, but also to various complications. The neurological complications may represent obstacles in patient management and require multidisciplinary collaboration. Although new methods of surgery, radiation therapy and pharmacotherapy have been designed in the last few years in order to prevent, mitigate, or manage the adverse effects of classical therapies, the overall survival of patients with BTs, especially glioblastoma (GB), remain poor. In this review we provide an overview of the most commo022328n neurological complications of BTs, as well as tumor therapies. We present what is already known on the topic but also the newest clinical data, and the results of clinical trials from the last few years. We also make a summary of the strategies capable of managing or even preventing these adverse effects.

Indexed as

Brain NeoplasmsGlioblastomaAntineoplastic AgentsClinical Trials as TopicCombined Modality TherapyHumansQuality of LifeAntineoplastic Agentsbrain tumorneurological complicationsstrategies to manage adverse effectstherapy

Identifiers

PMID42653393
PMCPMC13512941

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.