Evidence map›Paper›PMID 42653366›Full record

ArticleInternational journal of molecular sciences2026

Human Histatin 5 Exerts Anti-Trypanosomal Activity Against

Blanca Esther Blancas-Luciano, Ingeborg Becker, Marco Antonio Sánchez-Chávez, Aketzalli Gómez-Guzmán, Reyna Lara-Martínez, Luis Felipe Jiménez-García, Jaime Zamora-Chimal, José Delgado-Dominguez, Ana María Fernández-Presas

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Blanca Esther Blancas-LucianoDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0002-6985-1378
Ingeborg BeckerUnidad de Medicina Experimental, Universidad Nacional Autónoma de México, Hospital General de México "Dr. Eduardo Liceaga", Ciudad de México 06726, Mexico.ORCID 0000-0003-3821-4998
Marco Antonio Sánchez-ChávezDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Aketzalli Gómez-GuzmánDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.
Reyna Lara-MartínezDepartamento de Biología Celular y Tisular, Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0003-2708-573X
Luis Felipe Jiménez-GarcíaDepartamento de Biología Celular y Tisular, Facultad de Ciencias, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0003-2368-2975
Jaime Zamora-ChimalUnidad de Medicina Experimental, Universidad Nacional Autónoma de México, Hospital General de México "Dr. Eduardo Liceaga", Ciudad de México 06726, Mexico.ORCID 0000-0003-3690-0775
José Delgado-DominguezUnidad de Medicina Experimental, Universidad Nacional Autónoma de México, Hospital General de México "Dr. Eduardo Liceaga", Ciudad de México 06726, Mexico.ORCID 0000-0003-3570-3331
Ana María Fernández-PresasDepartamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México 04510, Mexico.ORCID 0000-0001-8180-7276

Funding

Universidad Nacional Autónoma de México FM/DI/035/2024
6 · The paper itself

Abstract

Chagas disease, caused by

Indexed as

ApoptosisHistatinsNitrosative StressOxidative StressTrypanocidal AgentsTrypanosoma cruziAnimalsChagas DiseaseChlorocebus aethiopsHumansMiceRAW 264.7 CellsReactive Oxygen SpeciesVero CellsHistatinsHTN3 protein, humanReactive Oxygen SpeciesTrypanocidal AgentsepimastigotesHistatin 5Trypanosoma cruzi

Identifiers

PMID42653366
PMCPMC13513000

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.