Evidence map›Paper›PMID 42653351›Full record

ReviewInternational journal of molecular sciences2026

Recent Advances in Therapy for the Neurodegenerative Disorder Ataxia-Telangiectasia.

Sam Nayler, Simon Foster, Martin Lavin, David Coman

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sam NaylerQIMR Berghofer Research Institute, Brisbane, QLD 4006, Australia.
Simon FosterQIMR Berghofer Research Institute, Brisbane, QLD 4006, Australia.ORCID 0000-0003-3034-1351
Martin LavinFrazer Institute, University of Queensland, Royal Brisbane and Women's Hospital, Herston, QLD 4029, Australia.
David ComanDepartment of Paediatrics, Wesley Medical Research, Auchenflower, Brisbane, QLD 4066, Australia.ORCID 0000-0001-6303-6471

Funding

Bellberry Ltd-Viertel Foundation Senior Medical Research Fellowship no. ViertelSMRF23013BrAshA-T, Action for A-T no. 22QIMR01Medical Research Future Fund Australia no. GA89314Wesley Research Institute
6 · The paper itself

Abstract

At present, there is no cure for the human genetic disorder ataxia-telangiectasia (A-T), which is managed by supportive care. This disorder arises due to mutations in the

Indexed as

Ataxia TelangiectasiaGenetic TherapyNeurodegenerative DiseasesAnimalsAtaxia Telangiectasia Mutated ProteinsDNA DamageHumansMutationOligonucleotides, AntisenseReactive Oxygen SpeciesAtaxia Telangiectasia Mutated ProteinsATM protein, humanOligonucleotides, AntisenseReactive Oxygen SpeciesASOA-TataxiaATMcerebellumDNA repairmitochondriaROStelangiectasiatherapy

Identifiers

PMID42653351
PMCPMC13512938

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.