Evidence map›Paper›PMID 42653298›Full record

ArticleInternational journal of molecular sciences2026

A Family Exhibiting Autosomal Dominant Inheritance of Multiple Acyl-Coenzyme A (CoA) Dehydrogenase Deficiency (MADD) Disease.

Francesco Baldo, Elena Genova, Valeria Capaci, Irene Marrone, Nour Balasan, Anna Monica Bianco, Luisa Zupin, Irene Bruno, Maria Teresa Bonati, Fulvio Celsi

Abstract readCase Reports
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Francesco BaldoDivision of Metabolic Diseases and Hepatology, Bambino Gesù Childrens Hospital IRCCS, 00165 Rome, Italy.ORCID 0000-0002-7523-3154
Elena GenovaInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-6692-6573
Valeria CapaciInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-0110-5942
Irene MarroneInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0009-0005-0673-7278
Nour BalasanInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Anna Monica BiancoInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-8101-9659
Luisa ZupinInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-5886-9129
Irene BrunoInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.
Maria Teresa BonatiInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0001-8024-0482
Fulvio CelsiInstitute for Maternal and Child Health-IRCCS "Burlo Garofolo", 34137 Trieste, Italy.ORCID 0000-0002-9760-8463

Funding

italian Health Ministry RC06/24
6 · The paper itself

Abstract

Multiple acyl-CoA dehydrogenase deficiency (MADD) is considered an autosomal recessive disorder; yet, recent findings suggest up to 10% of cases may result from heterozygous electron transfer flavoprotein dehydrogenase (

Indexed as

Electron-Transferring FlavoproteinsGenes, DominantIron-Sulfur ProteinsMultiple Acyl Coenzyme A Dehydrogenase DeficiencyOxidoreductases Acting on CH-NH Group DonorsFemaleFibroblastsHumansMaleModels, MolecularMutationPedigreeRiboflavinelectron-transferring-flavoprotein dehydrogenaseElectron-Transferring FlavoproteinsIron-Sulfur ProteinsOxidoreductases Acting on CH-NH Group DonorsRiboflavinautosomal dominantelectron transfer flavoprotein dehydrogenase (ETFDH)fatty acid metabolismmuscle weaknessprimary fibroblastsriboflavin

Identifiers

PMID42653298
PMCPMC13513812

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.