ArticleInternational journal of molecular sciences2026
Levels of ER Stress Markers GRP78, CHOP, and PERK in Cardiovascular Diseases.
Tülay Oskay, Alten Oskay, Mert Özen, Isık Tekin, Fırat Okta, Abdo A Elfiky, Murat Seyit, Atakan Yılmaz, Hakan Akça, Ibrahim Türkçüer and 4 more
Abstract read
In one paragraphArticle in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
14 authors.
Tülay OskayDepartment of Cardiology, Denizli State Hospital, 20010 Denizli, Türkiye.
Alten OskayDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0000-0003-4373-6280 Mert ÖzenDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.
Isık TekinDepartment of Cardiology, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0000-0003-2151-920X Fırat OktaDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0009-0001-0759-3211 Murat SeyitDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0000-0002-8324-9471 Atakan YılmazDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.
Hakan AkçaDepartment of Medical Genetics, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.
Ibrahim TürkçüerDepartment of Emergency Medicine, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0000-0001-8342-4615 Gergana LengerovaMicrobiology Laboratory, Department of Microbiology, Virology, Clinical Laboratory and Immunology, Military Medical Academy of Sofia, 1000 Sofia, Bulgaria.ORCID 0000-0003-0997-1439 Martina BozhkovaDepartment of Medical Microbiology and Immunology "Prof. Dr. Elissay Yanev", Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-4230-3299 Steliyan PetrovDepartment of Medical Microbiology and Immunology "Prof. Dr. Elissay Yanev", Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.ORCID 0000-0003-0522-5682 Aylin KöselerDepartment of Biophysics, Faculty of Medicine, Pamukkale University, 20160 Denizli, Türkiye.ORCID 0000-0003-4832-0436 Funding
Personalized Innovative Medicine Competence Center-2 BG16RFPR002-1.014-0007-C01
6 · The paper itselfAbstract
Cardiovascular diseases remain the leading cause of mortality worldwide, and endoplasmic reticulum (ER) stress has emerged as an important molecular mechanism underlying myocardial injury and heart failure. This study investigated the expression of the ER stress-related genes GRP78, PERK, and CHOP in peripheral whole blood obtained from patients with acute cardiovascular diseases. A total of 300 participants were enrolled, including 200 patients with ST-segment elevation myocardial infarction (STEMI,
Indexed as
Cardiovascular DiseaseseIF-2 KinaseEndoplasmic Reticulum StressHeat-Shock ProteinsTranscription Factor CHOPAgedBiomarkersCase-Control StudiesEndoplasmic Reticulum Chaperone BiPFemaleHumansMaleMiddle AgedBiomarkersDDIT3 protein, humanEIF2AK3 protein, humaneIF-2 KinaseEndoplasmic Reticulum Chaperone BiPHeat-Shock ProteinsHSPA5 protein, humanTranscription Factor CHOPCHOPER stressGRP78heart failuremyocardial infarctionPERK
Identifiers
PMID42653250
PMCPMC13513394
What OpenQuestion holds
Textmetadata
Read underepoch 390