Evidence map›Paper›PMID 42653209›Full record

ReviewInternational journal of molecular sciences2026

Fibrotic-Angiogenic Signaling Networks in Oral Submucous Fibrosis: Pathobiology and Therapeutic Targeting.

Samar Kamran, Nabeel Reza, Zurairah Berahim, Saeed Ur Rahman, Johari Yap Abdullah

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Samar KamranSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Nabeel RezaSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0009-0007-0393-9573
Zurairah BerahimSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.
Saeed Ur RahmanOral Biology, Institute of Basic Medical Sciences, Khyber Medical University, Peshawar 25000, Pakistan.
Johari Yap AbdullahSchool of Dental Sciences, Health Campus, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia.ORCID 0000-0002-6147-4192

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oral submucous fibrosis (OSMF) is a chronic, progressive fibrotic disorder with significant malignant potential, and limited effective treatments due to an incomplete understanding of its underlying molecular mechanisms. This narrative review synthesizes current evidence on the key molecular networks involved in OSMF pathogenesis, highlighting the central role of the

Indexed as

AngiogenesisNeovascularization, PathologicOral Submucous FibrosisSignal TransductionAnimalsConnective Tissue Growth FactorHumansTransforming Growth Factor beta1Connective Tissue Growth FactorTransforming Growth Factor beta1and COL1A1 signalingCTGFepithelial dysregulationfibrosis–angiogenesis interactionmalignant transformationoral submucous fibrosisprecision medicineTGF-β

Identifiers

PMID42653209
PMCPMC13513526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.