Evidence map›Paper›PMID 42653189›Full record

ArticleInternational journal of molecular sciences2026

Genetic Encoding of 3-Cyano-Tyrosine and Its Use in Controlling the Chromophore Isomeric State of the Fluorescent Protein mKate.

Connor J Stevenson, John J K McLarnon, James Harnedy, Salma A Elsherbeni, Debarshi Saha, Wolfgang Langbein, Paola Borri, Jamie A Platts, Louis C Morril, D Dafydd Jones

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Connor J StevensonMolecular Bioscience, School of Biosciences, Cardiff University, Sir Martin Evans Building, Cardiff CF10 3AX, UK.
John J K McLarnonMolecular Bioscience, School of Biosciences, Cardiff University, Sir Martin Evans Building, Cardiff CF10 3AX, UK.ORCID 0009-0008-6962-1645
James HarnedySchool of Chemistry, Cardiff University, Cardiff CF10 3AT, UK.
Salma A ElsherbeniSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, UK.ORCID 0009-0007-7265-7887
Debarshi SahaDepartment of Chemistry, University of Bath, Bath BA2 7AY, UK.
Wolfgang LangbeinSchool of Physics and Astronomy, Cardiff University, Cardiff CF24 3AA, UK.
Paola BorriMolecular Bioscience, School of Biosciences, Cardiff University, Sir Martin Evans Building, Cardiff CF10 3AX, UK.
Jamie A PlattsSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, UK.ORCID 0000-0002-1008-6595
Louis C MorrilSchool of Chemistry, Cardiff University, Cardiff CF10 3AT, UK.
D Dafydd JonesMolecular Bioscience, School of Biosciences, Cardiff University, Sir Martin Evans Building, Cardiff CF10 3AX, UK.ORCID 0000-0001-7709-3995

Funding

Biotechnology and Biological Sciences Research Council BB/Z514913/1Engineering and Physical Sciences Research Council EP/S023437/1Engineering and Physical Sciences Research Council EP/V048147/1European Research Council EP/Z001021/1
6 · The paper itself

Abstract

Switchable β-barrel-type fluorescent proteins are essential genetically encoded probes for super-resolution imaging. The space required for chromophore

Indexed as

Luminescent ProteinsTyrosineHydrogen-Ion ConcentrationIsomerismModels, MolecularRed Fluorescent ProteinLuminescent ProteinsmKateRed Fluorescent ProteinTyrosinechromophore isomerisationdensity functional theoryexpanded genetic codefluorescent proteinsprotein engineering

Identifiers

PMID42653189
PMCPMC13512924

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.