Evidence map›Paper›PMID 42653186›Full record

ArticleInternational journal of molecular sciences2026

Evidence for Altered Epigenetic Regulatory Machinery in Migraine: A Peripheral Blood Study.

Michal Fila, Kinga Kołacz-Milewska, Małgorzata Grygiel, Lukasz Przysło, Karolina Tworek, Agnieszka Robaszkiewicz, Maksim Ionov, Janusz Blasiak

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michal FilaDepartment of Developmental Neurology and Epileptology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.ORCID 0000-0002-0748-7080
Kinga Kołacz-MilewskaLaboratory of Microscopic Imaging and Specialized Biological Techniques, University of Lodz, 90-237 Lodz, Poland.
Małgorzata GrygielDepartment of General Biophysics, University of Lodz, 90-237 Lodz, Poland.
Lukasz PrzysłoDepartment of Developmental Neurology and Epileptology, Polish Mother's Memorial Hospital Research Institute, 93-338 Lodz, Poland.ORCID 0000-0003-0209-4103
Karolina TworekFaculty of Medicine and Health Sciences, Calisia University, 62-800 Kalisz, Poland.ORCID 0009-0008-9833-0935
Agnieszka RobaszkiewiczDepartment of General Biophysics, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0002-6265-5585
Maksim IonovDepartment of General Biophysics, University of Lodz, 90-237 Lodz, Poland.ORCID 0000-0001-7227-6864
Janusz BlasiakFaculty of Medicine, Collegium Medicum, Mazovian University in Plock, 09-402 Plock, Poland.ORCID 0000-0001-9539-9584

Funding

Ministry of Science and Higher Education PMMH-RI number 2023.2/5/5-GW
6 · The paper itself

Abstract

Calcitonin gene-related peptide (CGRP), encoded by the

Indexed as

Calcitonin Gene-Related PeptideEpigenesis, GeneticMigraine DisordersTRPA1 Cation ChannelAdultDNA MethylationFemaleGene Expression RegulationHistone Deacetylase 1Histone Deacetylase 6HumansMaleMicroRNAsMiddle AgedCalcitonin Gene-Related PeptideHDAC1 protein, humanHDAC6 protein, humanHistone Deacetylase 1Histone Deacetylase 6MicroRNAsMIRN34 microRNA, humanTRPA1 Cation ChannelTRPA1 protein, humanCGRPepigeneticsHDAC1HDAC6migrainesystemic alterations in migraineTRPA1

Identifiers

PMID42653186
PMCPMC13513782

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.