Evidence map›Paper›PMID 42653185›Full record

ArticleInternational journal of molecular sciences2026

Tear Cytokine Signature in Vernal Keratoconjunctivitis: A Chemokine-Remodeling Axis Associated with Disease Severity.

Kartik Goel, Mehak Sapra, Prisha Warikoo, Shailja Tibrewal, Hirak Patra, Virender Singh Sangwan, Abha Gour, Anil Tiwari

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kartik GoelEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.ORCID 0009-0008-6049-183X
Mehak SapraEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.
Prisha WarikooEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.ORCID 0009-0007-7423-1425
Shailja TibrewalDepartment of Ocular Genetics and Centre for Unknown and Rare Eye Diseases, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.
Hirak PatraDepartment of Surgical Biotechnology, Division of Surgery and Interventional Science, University College London, London NW3 2PS, UK.ORCID 0000-0002-6142-5489
Virender Singh SangwanEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.ORCID 0000-0002-8229-4158
Abha GourEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.
Anil TiwariEicher Shroff Centre for Stem Cell Research, Dr. Shroff's Charity Eye Hospital, New Delhi 110002, India.

Funding

Department of Biotechnology BTHRD/35/02/2006Velux Stiftung 1973
6 · The paper itself

Abstract

Vernal keratoconjunctivitis (VKC) is a chronic pediatric ocular allergy that can progress from seasonal to persistent inflammation with vision-threatening complications. Although Th2-associated mechanisms have been implicated, the immune correlates of disease severity are not well defined. Tear samples from VKC patients (moderate intermittent and moderate persistent) and healthy controls were collected using Schirmer's strips. Cytokine profiling was performed using the OLINK

Indexed as

ChemokinesConjunctivitis, AllergicCytokinesTearsAdolescentBiomarkersChildFemaleHumansMaleSeverity of Illness IndexSignal TransductionBiomarkersChemokinesCytokinescytokinesocular allergytear proteomicsvernal keratoconjunctivitis

Identifiers

PMID42653185
PMCPMC13513524

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.