Evidence map›Paper›PMID 42653135›Full record

ReviewInternational journal of molecular sciences2026

Cold Atmospheric Plasma in Wound Healing: Molecular Mechanism of Action.

Dawid Bińkowski, Bogusław Antoszewski, Anna Kasielska-Trojan

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dawid BińkowskiFaculty of Medicine, Medical University of Lodz, 90-419 Lodz, Poland.ORCID 0009-0006-8778-6510
Bogusław AntoszewskiPlastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, 90-153 Lodz, Poland.ORCID 0000-0003-3197-8223
Anna Kasielska-TrojanPlastic, Reconstructive and Aesthetic Surgery Clinic, Institute of Surgery, Medical University of Lodz, 90-153 Lodz, Poland.ORCID 0000-0002-2542-8623

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cold atmospheric plasma (CAP) is a promising tool used in medicine due to its broad spectrum of biological activity and the possibility of safe application on living tissues without the risk of thermal damage. CAP is a partially ionised gas containing electrons, ions and reactive oxygen and nitrogen species (RONS); it also emits ultraviolet radiation and an electromagnetic field. The aim of this study is to discuss the mechanisms of action of cold atmospheric plasma and to assess its significance in supporting the skin healing process. Analysis of the available data indicates that CAP acts in multiple ways: it stimulates the proliferation and migration of keratinocytes and fibroblasts, modulates the inflammatory response, exhibits antimicrobial properties, and improves microcirculation and enhances angiogenesis. The results of studies to date suggest that cold atmospheric plasma may provide valuable support for therapies, particularly in the context of skin regeneration, wound healing and the treatment of inflammatory lesions. However, further research is needed on the standardisation of treatment parameters, long-term safety, and the precise definition of indications and contraindications depending on the type of device used.

Indexed as

Plasma GasesWound HealingAnimalsCell ProliferationFibroblastsHumansKeratinocytesReactive Oxygen SpeciesSkinPlasma GasesReactive Oxygen Speciescold atmospheric plasmaplasmaplasma medicinereactive oxygen and nitrogen speciesregenerative medicinewound healing

Identifiers

PMID42653135
PMCPMC13513933

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.