Evidence map›Paper›PMID 42653124›Full record

ArticleInternational journal of molecular sciences2026

Heterogeneous CRISPR/Cas9 Editing of

Haonan Tang, Huaiyu Li, Yurong Tai, Xue Yang, Letian Zhang, Yuhao Ma, Ganxian Cai, Hongyang Zhao, Tong Zeng, Xiaohua Ai and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Haonan TangKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Huaiyu LiKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Yurong TaiKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Xue YangKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Letian ZhangKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Yuhao MaKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Ganxian CaiKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Hongyang ZhaoKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Tong ZengKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Xiaohua AiKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Shuang HeKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Jiankui WangKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.
Zhiliang GuCollege of Biology and Food Engineering, Suzhou University of Technology, Suzhou 215500, China.
Xuemei DengKey Laboratory of Animal Genetics, Breeding and Reproduction, Ministry of Agriculture, Beijing Key Laboratory for Animal Genetic Improvement, State Key Laboratory of Animal Biotech Breeding, China Agricultural University, Beijing 100193, China.

Funding

Department of Science and Technology of Shandong Province 2022LZGCQY016Jiangxi Provincial Joint Research Project 2022JXCQZY05National Natural Science Foundation of China 32472896the National Joint Breeding Research Project. Additional support was provided by the 2115 Talent Development Program of China Agricultural University
6 · The paper itself

Abstract

Heme oxygenase-1 (HO-1), encoded by

Indexed as

BiliverdineCRISPR-Cas SystemsGene EditingHemeHeme Oxygenase-1Stress, PhysiologicalAnimalsCell Line, TumorChickensTranscription, GeneticBiliverdineHemeHeme Oxygenase-1biliverdinchicken LMH cellsCRISPR/Cas9heme metabolismheme oxygenase-1HMOX1immune signalingoxidative stress

Identifiers

PMID42653124
PMCPMC13513460

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.