Evidence map›Paper›PMID 42653096›Full record

ArticleInternational journal of molecular sciences2026

Swimming in Plastamination: Polylactic Acid (PLA) Nanoplastics Affect Bull Sperm Functions.

Alessia Gloria, Massimo Venditti, Erwin Pavel Lamparelli, Maria Zelinda Romano, Giovanna Della Porta, Andrea Viggiano, Antonietta Santoro, Alberto Contri, Rosaria Meccariello

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessia GloriaDepartment of Veterinary Medicine, University of Teramo, Loc. Piano d'Accio, 64100 Teramo, Italy.
Massimo VendittiDepartment of Experimental Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-7357-5353
Erwin Pavel LamparelliDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Salerno, Italy.
Maria Zelinda RomanoDepartment of Medical, Human Movement and Well-Being Sciences, University of Naples Parthenope, 80133 Naples, Italy.ORCID 0000-0001-9378-178X
Giovanna Della PortaDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Salerno, Italy.ORCID 0000-0002-1426-0159
Andrea ViggianoDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Salerno, Italy.
Antonietta SantoroDepartment of Medicine, Surgery and Dentistry, University of Salerno, 84081 Baronissi, Salerno, Italy.ORCID 0000-0002-2549-5447
Alberto ContriDepartment of Veterinary Medicine, University of Teramo, Loc. Piano d'Accio, 64100 Teramo, Italy.ORCID 0000-0002-1527-3285
Rosaria MeccarielloDepartment of Medical, Human Movement and Well-Being Sciences, University of Naples Parthenope, 80133 Naples, Italy.ORCID 0000-0003-2174-1118

Funding

European Union-Next Generation EU", M4.C2., Investment 1.1, "Fund for the National Research Program and Projects of Relevant National Interest", PRIN-PNRR2022: Project title: Poly (Lactic Acid) plastics contamination (PLASTAMINATION): organ injuries and u P2022AA47Y
6 · The paper itself

Abstract

Plastic contamination (plastamination) is one of the main challenges of the 21st century. Microplastics (MPs, 5 mm-1 µm) and nanoplastics (NPs, <1 µm) are mainly produced from the environmental degradation of plastic waste and enter the food chain, bypass biological barriers, and bioaccumulate in tissues where they exert toxic/inflammatory effects. In the male reproductive system, MP/NPs can cross the blood-testis barrier, impair spermatogenesis, and affect semen quality parameters. While biodegradable polymers like polylactic acid (PLA) may represent an ecofriendly alternative to carbon fossil polymers, their real effects in reproduction have been poorly investigated. In the present manuscript, the effects of increasing doses of rhodamine B-loaded PLA-NPs (170 ± 20 nm mean size) on the physiology of frozen-thawed bovine sperm were investigated using a computer-assisted sperm analyzer (CASA) and flow cytometry. Sperm kinetics revealed a significant effect of PLA-NPs on progressive motility at 60 min, with higher values at 200 and 300 µg/mL doses (

Indexed as

MicroplasticsNanoparticlesPolyestersSpermatozoaSperm MotilityAnimalsCattleMaleMembrane Potential, MitochondrialRhodaminesMicroplasticsPolyesterspoly(lactide)Rhodaminesbovinemicro and nano-plasticsplastic contaminationpolylactic acid (PLA)semen quality

Identifiers

PMID42653096
PMCPMC13512978

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.