Evidence map›Paper›PMID 42653093›Full record

ArticleInternational journal of molecular sciences2026

Bridging In Vitro Functionality and Genomic Insights in

Lili Dobreva, Nikoleta Atanasova, Petar Donchev, Ekaterina Krumova, Radoslav Abrashev, Maria Angelova, Greta Naydenova, Apostol Apostolov, Dragomir Yankov, Vladimir Tolchkov and 1 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Lili DobrevaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-7776-3554
Nikoleta AtanasovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0009-0007-6091-1817
Petar DonchevThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0009-0000-6724-4374
Ekaterina KrumovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0009-0004-0837-5584
Radoslav AbrashevThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.
Maria AngelovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0000-0003-0314-0837
Greta NaydenovaInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 103 Acad. G. Bontchev Str., 1113 Sofia, Bulgaria.
Apostol ApostolovInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 103 Acad. G. Bontchev Str., 1113 Sofia, Bulgaria.ORCID 0000-0002-6708-2640
Dragomir YankovInstitute of Chemical Engineering, Bulgarian Academy of Sciences, 103 Acad. G. Bontchev Str., 1113 Sofia, Bulgaria.ORCID 0000-0003-0433-7930
Vladimir TolchkovCenter of Competence "Immunopathogen", Yanko Sakuzov Blvd 26, 1504 Sofia, Bulgaria.
Svetla DanovaThe Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 26 Acad. G. Bonchev Str., 1113 Sofia, Bulgaria.ORCID 0009-0006-3921-3785

Funding

Project No. PVU-63 of 16.12.2024 BG-RRP-2.017-0047-C01 "New approaches for selection and integration of BIOTICS (pro/post and metabiotics) in functional formulas for food supplements with high biological potential based on agro and industrial waste", unde PVU-63 of 16.12.2024 BG-RRP-2.017-0047-C01
6 · The paper itself

Abstract

Katak, a traditional Bulgarian fermented dairy product distinguished by its unique sensory characteristics and extended shelf life, represents a valuable source of autochthonous microorganisms whose functional and genomic properties remain insufficiently explored. In the present study, strain L3, isolated from katak, was comprehensively characterized by a polyphasic approach integrating classical microbiological methods, molecular identification, and whole-genome sequencing. Functional assessment revealed a broad spectrum of antimicrobial activity against pathogenic bacteria and food-associated fungi, accompanied by pronounced radical-scavenging and antioxidant capacities. The strain also exhibited high transit tolerance in simulated gut passage and a favorable antibiotic susceptibility profile, indicating its potential as a probiotic candidate. Whole-genome sequencing confirmed the taxonomic affiliation of the isolate as

Indexed as

Cultured Milk ProductsGenome, BacterialLactiplantibacillus plantarumBulgariaGenomicsPhylogenyProbioticsWhole Genome Sequencingcandidate probiotickatakLactiplantibacillus plantarumwhole-genome sequencing

Identifiers

PMID42653093
PMCPMC13512861

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.