Evidence map›Paper›PMID 42653005›Full record

ArticleLife (Basel, Switzerland)2026

Prevalence and Correlates of Sinonasal Symptom Burden in Young Adult Males: A Cross-Sectional Population-Based Study (PrENT Study).

Emanuel Maitz, Reinhard Domanyi, Gerold Schwantzer, Gerald Sendlhofer, Alexandros Andrianakis, Dietmar Thurnher, Thomas Weiland

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emanuel MaitzDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, 8010 Graz, Austria.
Reinhard DomanyiDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, 8010 Graz, Austria.
Gerold SchwantzerInstitute for Medical Informatics, Statistics and Documentation, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0003-3349-1101
Gerald SendlhoferDivision of Plastic, Aesthetic and Reconstructive Surgery, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-6538-3116
Alexandros AndrianakisDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-2530-9931
Dietmar ThurnherDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, 8010 Graz, Austria.
Thomas WeilandDepartment of Otorhinolaryngology, Head and Neck Surgery, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-5501-1220

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesChronic rhinosinusitis (CRS) is a prevalent chronic inflammatory upper airway disease. Despite a higher radiological disease burden in males, clinical CRS diagnoses are disproportionately registered in females, suggesting systematic underdiagnosis in young men. The 22-item Sinonasal Outcome Test (SNOT-22) represents the reference patient-reported outcome measure (PROM) for sinonasal symptom burden. This study aimed to determine the prevalence of sinonasal symptom burden and to identify associated clinical, laboratory, and lifestyle parameters in a large cohort of young male adults.

methodsIn this prospective cross-sectional study, 500 young male adults underwent, as part of the conscription examination, standardized assessment including the SNOT-22, spirometry (FEV

resultsThe mean SNOT-22 score was 18.8 (SD 15.2; range 0-73). A total of 38.2% of participants scored ≥21, indicating at least moderate sinonasal symptom burden. SNOT-22 correlated significantly with CRP (r = 0.117,

conclusionsMore than one third of young male adults reported significant self-reported sinonasal symptom burden. Symptom severity was associated with systemic inflammatory markers and reduced pulmonary function, supporting the unified airway concept. These findings support the utility of SNOT-22 as a low-threshold assessment tool for self-reported sinonasal symptom burden in preventive health examinations.

Indexed as

chronic rhinosinusitisC-reactive proteineosinophilspopulation-based studySNOT-22spirometryunified airwayyoung adult males

Identifiers

PMID42653005
PMCPMC13514106

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.