Evidence map›Paper›PMID 42652969›Full record

ReviewLife (Basel, Switzerland)2026

Prevalence of Persistent Left Superior Vena Cava in Patients with Congenital Heart Disease: A Systematic Review with Meta-Analysis.

George Triantafyllou, Ioannis Paschopoulos, Daniel Gondorf, Niki Lama, Evangelos Oikonomou, Juan Jose Valenzuela-Fuenzalida, Juan Sanchis-Gimeno, Jose E León-Rojas, Charalambos Vlachopoulos, Gerasimos Siasos and 1 more

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

George TriantafyllouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0001-0122-2436
Ioannis PaschopoulosDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0000-6221-7537
Daniel GondorfDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0009-0006-4945-7062
Niki LamaResearch Unit of Radiology and Medical Imaging, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11528 Athens, Greece.
Evangelos OikonomouThird Department of Cardiology, Sotiria Chest Disease Hospital, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0001-8079-0599
Juan Jose Valenzuela-FuenzalidaFaculty of Medicine, Andrés Bello University, Santiago 8370146, Chile.
Juan Sanchis-GimenoGIAVAL Research Group, Department of Anatomy and Human Embryology, Faculty of Medicine, University of Valencia, 46001 Valencia, Spain.ORCID 0000-0002-2599-8474
Jose E León-RojasGrupo de Investigación Bienestar, Salud y Sociedad, Escuela de Psicología y Educación, Universidad de Las Américas, Quito 170124, Ecuador.ORCID 0000-0002-8130-6460
Charalambos VlachopoulosFirst Department of Cardiology, General Hospital of Athens "Hippokrateion", School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-9904-3558
Gerasimos SiasosThird Department of Cardiology, Sotiria Chest Disease Hospital, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Maria PiagkouDepartment of Anatomy, School of Medicine, Faculty of Health Sciences, National and Kapodistrian University of Athens, 11527 Athens, Greece.ORCID 0000-0002-4831-8005

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Persistent left superior vena cava (PLSVC) is the most frequently reported anatomical variant of the thoracic systemic venous system. While its association with congenital heart disease (CHD) is well recognized, its prevalence within CHD populations and its relative occurrence compared with non-CHD cohorts remain incompletely characterized. This study aimed to estimate the pooled prevalence of PLSVC among patients with CHD and to assess its relative frequency compared with that in control populations. A systematic review of PubMed, Scopus, and Web of Science was conducted from database inception to January 2026. Studies reporting the prevalence of PLSVC in CHD cohorts were included. A random-effects meta-analysis was performed, and risk ratios (RRs) were calculated for studies that included both CHD and non-CHD groups. Sixteen studies (

Indexed as

cardiologycongenital heart diseasesevidence-based anatomymeta-analysispersistent left superior vena cava

Identifiers

PMID42652969
PMCPMC13514220

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.