Evidence map›Paper›PMID 42652911›Full record

ArticleLife (Basel, Switzerland)2026

Non-Allergic Contact Dermatitis in Different Professions: The Analysis in the Triveneto Region (Northeast of Italy) Patch Test Database from 1997 to 2023.

Francesca Larese Filon, Elia Contento, Alice Tassinari, Sansone Donatella, Anna Belloni Fortina, Erika Giulioni, Marcella Mauro

Abstract read
In one paragraph

Article in Life (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Francesca Larese FilonUnit of Occupational Medicine, University of Trieste, Azienda Sanitaria Universitaria Giuliano Isontina, Via della Pietà 2/2, 34129 Trieste, Italy.ORCID 0000-0002-7717-0417
Elia ContentoUnit of Occupational Medicine, University of Trieste, Azienda Sanitaria Universitaria Giuliano Isontina, Via della Pietà 2/2, 34129 Trieste, Italy.
Alice TassinariUnit of Occupational Medicine, University of Trieste, Azienda Sanitaria Universitaria Giuliano Isontina, Via della Pietà 2/2, 34129 Trieste, Italy.ORCID 0009-0006-7182-5087
Sansone DonatellaUnit of Occupational Medicine, University of Trieste, Azienda Sanitaria Universitaria Giuliano Isontina, Via della Pietà 2/2, 34129 Trieste, Italy.
Anna Belloni FortinaClinica Dermatologica, University of Padua, Via Gallucci 4, 35121 Padova, Italy.ORCID 0000-0001-5791-0775
Erika GiulioniDermatology Unit, Ospedale Santa Maria Degli Angeli, Via Montereale 24, 33170 Pordenone, Italy.
Marcella MauroUnit of Occupational Medicine, University of Trieste, Azienda Sanitaria Universitaria Giuliano Isontina, Via della Pietà 2/2, 34129 Trieste, Italy.ORCID 0000-0003-1317-3448

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Contact dermatitis (CD) is one of the most common occupational skin diseases worldwide, and patch tests are used to identify allergic contact dermatitis (ACD). Half of the cases were negative for patch tests (non-ACD). In our study, we aim to analyze patch test negativity in different occupational groups from the Triveneto (northeast Italy) Patch Test Database and to identify associated demographic and exposure-related factors. Data from 31,948 patients evaluated for suspected ACD between 1997 and 2023 were analyzed. All participants underwent clinical examination, completed a standardized questionnaire, and underwent patch testing. Occupational categories and anatomical sites were aggregated into broader groups and analyzed with multivariable logistic regression models. Among 31,948 patients with CD, 43.4% had negative patch test results. The mean age was 43.8 ± 17.2 years, with a predominance of female patients (66.7%). Hands were the most affected body site (30.9%), with lower prevalence of patch test negativity (OR 0.936; 95% CI 0.892-0.981). Non-ACD was more frequent among non-workers as students (OR 1.380; 95% CI 1.192-1.597) and in occupational groups involved in wet work, detergent use, mechanical friction, and exposure to irritating substances such as mechanics (OR 1.152; 95%CI 1.018-1.204) and cooks with hand dermatitis (OR 1.784; 95%CI 1.936-3.071). These findings highlight the importance of non-ACD, the need for better prevention strategies, improved skin protection practices, and early recognition of irritant exposure in the workplace.

Indexed as

allergic contact dermatitisirritant contact dermatitisoccupationpatch test

Identifiers

PMID42652911
PMCPMC13514952

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.