Evidence map›Paper›PMID 42652358›Full record

ArticleInternational journal of environmental research and public health2026

Halitosis and Its Association with Sleep Quality and Psychological Factors Among University Students: A Cross-Sectional Study.

Juliana Maria Altavista Sagretti Gallo, Amanda Rafaelly Honório Mandetta, Ana Paula Taboada Sobral, Marcela Letícia Leal Gonçalves, Mayumi Oshiro Costa, Caroline Diniz Pagani Vieira Ribeiro, Mariana Moreira Machado, Abigail Malavasi, Elaine Marcílio Santos, Cinthya Cosme Gutierrez Duran and 1 more

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Article in International journal of environmental research and public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Juliana Maria Altavista Sagretti GalloAcademic Master's Program in Medicine in the Coastal Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.
Amanda Rafaelly Honório MandettaPostgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01504-001, Brazil.ORCID 0000-0001-7825-6725
Ana Paula Taboada SobralPostgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.ORCID 0000-0002-6846-6574
Marcela Letícia Leal GonçalvesPostgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.ORCID 0000-0003-1305-5257
Mayumi Oshiro CostaSchool of Psychology, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.ORCID 0009-0004-2071-1683
Caroline Diniz Pagani Vieira RibeiroPostgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01504-001, Brazil.
Mariana Moreira MachadoSchool of Medicine, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.ORCID 0009-0009-9960-3031
Abigail MalavasiProfessional Master's Program in Teaching Practices in Elementary Education, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.
Elaine Marcílio SantosPostgraduate Program in Health and Environment, Universidade Metropolitana de Santos (UNIMES), Santos 11045-002, Brazil.
Cinthya Cosme Gutierrez DuranPostgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01504-001, Brazil.ORCID 0000-0001-9055-1524
Sandra Kalil BussadoriPostgraduate Program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho (UNINOVE), São Paulo 01504-001, Brazil.

Funding

São Paulo Research Foundation #2022/16828-7
6 · The paper itself

Abstract

introductionHalitosis is a common oral condition that may negatively affect social interactions, psychological well-being, and quality of life. However, evidence regarding its association with mental health and sleep quality remains inconsistent, particularly among university students.

aimThis cross-sectional study investigated the prevalence of objectively measured halitosis and its association with tongue coating, sleep quality, and symptoms of anxiety, depression, and stress among university students from the metropolitan region of Santos, Brazil.

methodsSixty-two Brazilian university students enrolled in health-related undergraduate programs participated in the study; most were in the first academic year (61.3%) and resided in the municipality of Santos (59.7%). Halitosis was assessed using a portable breath detector, tongue coating was evaluated using the Coated Tongue Index, sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI), and symptoms of depression, anxiety, and stress were measured using the Depression, Anxiety and Stress Scale (DASS-21).

resultsObjectively measured halitosis was identified in 25 participants (40.3%; 95% CI: 29.0-52.7%). The analyses did not provide statistically significant evidence of associations between objectively measured halitosis and tongue coating, sleep quality, or symptoms of anxiety, depression, and stress. Significant positive correlations were identified between stress and sleep disturbance, anxiety and sleep disturbance, and depression and sleep latency, daytime dysfunction, and overall sleep quality. Tongue-cleaning habits were significantly associated with the presence of halitosis, whereas oral mucosal desquamation was less frequent among participants with halitosis.

conclusionThe study did not provide statistically significant evidence of associations between objectively measured halitosis and tongue coating, sleep quality, or psychological symptoms in this population. Significant positive correlations were identified between stress and sleep disturbance, anxiety and sleep disturbance, and depression and sleep latency, daytime dysfunction, and overall sleep quality. These findings highlight the importance of objectively assessing oral malodor in epidemiological studies.

Indexed as

HalitosisSleep QualityStudentsAdolescentAdultAnxietyBrazilCross-Sectional StudiesDepressionFemaleHumansMalePrevalenceStress, PsychologicalUniversitiesYoung Adultanxietydepressionhalitosissleep qualitystressuniversity students

Identifiers

PMID42652358
PMCPMC13512801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.