Evidence map›Paper›PMID 42652051›Full record

ArticleBiomedicines2026

Myeloid GHSR Deficiency Protects Against Endotoxemia via Macrophage Mitochondrial Reprogramming.

Da Mi Kim, Zheng Shen, Quan Pan, Zeyu Liu, Wanbao Yang, Natividad R Fuentes, Robert S Chapkin, Gus A Wright, Bhimanagouda Patil, Shaodong Guo and 1 more

Abstract read
In one paragraph

Article in Biomedicines, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Da Mi KimDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-2445-8289
Zheng ShenDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0002-0523-0767
Quan PanDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-8327-9657
Zeyu LiuDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0009-0005-3416-6783
Wanbao YangDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.
Natividad R FuentesDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-9571-808X
Robert S ChapkinDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.
Gus A WrightDepartment of Veterinary Pathobiology, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0003-4010-7825
Bhimanagouda PatilVegetable and Fruit Improvement Center, Department of Horticultural Sciences, Texas A&M University, College Station, TX 77845, USA.
Shaodong GuoDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.ORCID 0000-0001-5126-731X
Yuxiang SunDepartment of Nutrition, Texas A&M University, College Station, TX 77843, USA.

Funding

Texas A&M Center for Environmental Health Research (TiCER)P30ES029067 · NIEHS · TEXAS A&M UNIVERSITY · PI Sakhila Banu · 2019 to 2026
$13.0M
Nutrient-sensing GHS-R in macrophage reprogramming and inflamm-agingR01AG064869 · NIA · TEXAS A&M AGRILIFE RESEARCH · PI SUN, YUXIANG · 2019 to 2023
$2.1M
Hepatic TGFbeta1 in Control of Type 2 Diabetes and NASH via FoxO1 SignalingR01DK124588 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI GUO, SHAODONG · 2022 to 2025
$2.0M
The role of GHS-R in macrophage reprogramming during meta-inflammationR01DK118334 · NIDDK · TEXAS A&M AGRILIFE RESEARCH · PI SUN, YUXIANG · 2019 to 2022
$1.2M
Allen Endowed Chair in Nutrition & Chronic Disease Prevention N/ACancer Prevention and Research Institute of Texas (CPRIT) RP250537Cancer Prevention and Research Institute of Texas (CPRIT) RP250641NIA NIH HHS R01 AG064869NIDDK NIH HHS R01 DK118334NIDDK NIH HHS R01 DK124588NIEHS NIH HHS P30 ES029067NIH HHS 2P30ES029067-06NIH HHS 5R01AG064869-02NIH HHS 5R01DK118334-04NIH HHS 5R01DK124588-04Texas A&M AgriLife Institute for Advancing Health Through Agriculture (IHA) 58-3091-1-018Texas A&M University Division of Research Targeted Proposal Teams (TPT) N/AUnited States Department of Agriculture (USDA) Hatch 7001445United States Department of Agriculture (USDA) Multistate Research Fund 7008794
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

endotoxemiagrowth hormone secretagogue receptor (GHSR)lipopolysaccharide (LPS)macrophagemitochondrial functionreactive oxygen species (ROS)

Identifiers

PMID42652051
PMCPMC13509658

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.