Evidence map›Paper›PMID 42652020›Full record

ArticleAnimals : an open access journal from MDPI2026

Mechanism of Silybin in Alleviating Liver Damage Induced by Heat Stress of Peking Ducks.

Ziyue Zhang, Shihao Xuan, Junfeng Lv, Zhaofei Xia, Dong Zhang, Jing Chen, Zouran Lan, Guisheng Wang, Yanhan Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ziyue ZhangShandong Vocational Animal Science and Veterinary College, Weifang 261061, China.
Shihao XuanCollege of Veterinary Medicine, Shandong Agricultural University, Taian 271018, China.
Junfeng LvPoultry Institute, Shandong Academy of Agricultural Sciences, Jinan 250100, China.
Zhaofei XiaCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.
Dong ZhangShandong Provincial Center for Animal Disease Control, Jinan 250100, China.
Jing ChenShandong Provincial Center for Animal Disease Control, Jinan 250100, China.
Zouran LanShandong Provincial Center for Animal Disease Control, Jinan 250100, China.
Guisheng WangShandong Provincial Center for Animal Disease Control, Jinan 250100, China.
Yanhan LiuCollege of Veterinary Medicine, China Agricultural University, Beijing 100193, China.

Funding

Shandong Provincial Rural Revitalization Science and Technology Innovation Boosting Action Program 2025TZXD023
6 · The paper itself

Abstract

This study aimed to explore the protective mechanism of silybin against heat stress-induced liver injury in Peking ducks as a result of oxidative stress, inflammation, and lipid metabolism. One hundred and ninety-five 1-day-old healthy male Peking ducks with similar body weights were randomly divided into a control group, a heat-stress group, and three intervention groups treated with 400, 800, and 1600 mg/kg silybin under heat-stress from 21 d to 35 d for two weeks. The function indices, oxidative stress, inflammatory factor levels, histopathological changes and non-targeted lipidomic profiling in liver as well as growth performance were evaluated. Results showed that silybin supplementation partially alleviated the heat-stress-induced decreases in average daily feed intake and body weight gain (

Indexed as

heat stressliverpeking duckssilybintranscriptome

Identifiers

PMID42652020
PMCPMC13509931

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.