Evidence map›Paper›PMID 42651970›Full record

ArticleAnimals : an open access journal from MDPI2026

Histological and Strand-Specific Transcriptomic Analyses Reveal Developmental Dynamics and Pigmentation-Associated Candidate Genes in Black and White Skin Regions of Bama Miniature Pigs.

Lingli Feng, Qin Xia, Wenwen Xu, Zhongrong Deng, Alida Abla, Jiafu Li, Jinning Liang, Yanping Zhang, Xiaoping Guo, Jing Liang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lingli FengLiangzhu Laboratory, Zhejiang University School of Medicine, Zhejiang University, Hangzhou 311100, China.ORCID 0000-0002-9818-3217
Qin XiaGuangxi Key Laboratory of Animal Breeding and Disease Control, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Wenwen XuInstitute of Animal Husbandry, Guangxi Vocational University of Agriculture, Nanning 530007, China.
Zhongrong DengGuangxi Key Laboratory of Animal Breeding and Disease Control, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Alida AblaGuangxi Key Laboratory of Animal Breeding and Disease Control, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0009-0003-3576-3219
Jiafu LiLaboratory Animal Center, Guangxi Medical University, Nanning 530021, China.
Jinning LiangLaboratory Animal Center, Guangxi Medical University, Nanning 530021, China.
Yanping ZhangGuangxi Key Laboratory of Animal Breeding and Disease Control, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Xiaoping GuoLaboratory Animal Center, Guangxi Medical University, Nanning 530021, China.
Jing LiangGuangxi Key Laboratory of Animal Breeding and Disease Control, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0001-5533-2107

Funding

China National Center for Biotechnology Development 2024YFD1300701Department of Education of Guangxi Zhuang Autonomous Region 2024KY1248Guangxi Center for Disease Prevention and Control ABDC-b202502
6 · The paper itself

Abstract

Guangxi Bama miniature pigs are a highly inbred population developed from Bama Xiang pigs and exhibit a stable "two-end black" skin phenotype, making them a useful model for studying regional skin pigmentation. However, the developmental timing and molecular basis of this color difference remain unclear. In this study, black and white skin samples were collected from the posterior head/neck region at six developmental stages: embryonic days 65, 90, and 105, birth, and postnatal days 30 and 180. Histological examination and strand-specific RNA sequencing showed that developmental stage was the major factor shaping skin gene expression, whereas black-white skin differences varied across stages. Transcriptomic differences were already detectable at embryonic day 65, although visible regional differences were not obvious. Pigmentation-associated genes, including

Indexed as

Bama miniature pigblack skinpigmentationRNA-seqwhite skin

Identifiers

PMID42651970
PMCPMC13508850

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.