ArticleAnimals : an open access journal from MDPI2026
Investigation into the Short-Term Effects of Intra-Articular Allogenic PRP in the Equine LPS Model of Joint Inflammation: A Randomised Control Trial.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
7 authors.
Funding
Abstract
This study aimed to investigate the effects of allogenic platelet-rich plasma (PRP) injection in lipopolysaccharide (LPS) inflamed equine radiocarpal joints. A preliminary study using a 0.0625 ng LPS dose was performed in the middle carpal joint and compared within animal to a saline control to confirm that synovitis was consistently produced using this dose. The main PRP effect study involved a bilateral 0.0625 ng LPS inflammation model with a within-animal comparison of LPS plus PRP versus a LPS plus saline control. Serial synovial fluid analysis was performed on samples obtained at post-injection hours (PIH) 0, 8, 24, 72, and 168. Synovial fluid analysis and clinical parameters were further complimented by objective gait and thermographic analyses. The 0.0625 ng dose induced a statistically significant increase in the synovial TP and WBC concentrations from baseline (
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