ArticleAnimals : an open access journal from MDPI2026
Differential Serum Cytokine Profiles in Aborting and Subclinically Infected Pregnant Mares with Equine Herpesvirus Type 1.
Article in Animals : an open access journal from MDPI, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
12 authors.
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Abstract
Equine herpesvirus type 1 (EHV-1) is a major cause of reproductive loss in mares. This cross-sectional field study evaluated serum concentrations of interleukin-2 (IL-2), interleukin-10 (IL-10), interferon-alpha (IFN-α), and interferon-gamma (IFN-γ), together with the IL-10/IL-2 and IFN-γ/IL-10 ratios, in 26 vaccinated pregnant Thoroughbred mares. The analytical cohort comprised healthy, EHV-1 PCR-negative mares (HM, n = 10), EHV-1 PCR-positive mares sampled within 4 h after fetal expulsion at approximately the sixth month of gestation (AM, n = 9), and EHV-1 PCR-positive pregnant mares without clinically relevant signs (WCS, n = 7). EHV-1 DNA was detected using an EHV-1-specific real-time PCR assay, and serum cytokine concentrations were measured using equine-specific ELISA kits. Serum IFN-α, IFN-γ, and IL-2 concentrations were significantly higher in both AM and WCS mares than in HM mares (all Holm-adjusted
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