Evidence map›Paper›PMID 42651842›Full record

ReviewCurrent issues in molecular biology2026

Magnesium Sulfate in Neonatal Hypoxic-Ischemic Encephalopathy: Bridging the Gap Between Molecular Neuroprotection and Clinical Outcomes.

Maria Ester Canepa, Federico Prefumo, Pasquale Striano, Andrea Calandrino, Luca Antonio Ramenghi

Abstract readReview
In one paragraph

Review in Current issues in molecular biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maria Ester CanepaDepartment of Neuroscience, Ophthalmology, Genetics and Mother-Child Health, University of Genoa, 16148 Genoa, Italy.ORCID 0009-0004-7400-1724
Federico PrefumoObstetrics and Gynecology Unit, IRCCS Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0001-7793-714X
Pasquale StrianoDepartment of Neuroscience, Ophthalmology, Genetics and Mother-Child Health, University of Genoa, 16148 Genoa, Italy.ORCID 0000-0002-6065-1476
Andrea CalandrinoDepartment of Neuroscience, Ophthalmology, Genetics and Mother-Child Health, University of Genoa, 16148 Genoa, Italy.ORCID 0000-0002-2710-1798
Luca Antonio RamenghiDepartment of Neuroscience, Ophthalmology, Genetics and Mother-Child Health, University of Genoa, 16148 Genoa, Italy.ORCID 0000-0003-0065-762X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal hypoxic-ischemic encephalopathy (HIE) remains one of the leading causes of neonatal mortality and long-term neurodevelopmental disability despite therapeutic hypothermia, which provides only partial neuroprotection. Among adjunctive therapies, magnesium sulfate (MgSO

Indexed as

excitotoxicityHypoxic–ischemic encephalopathymagnesium sulfateneuroinflammationneuroprotectionNMDA receptortherapeutic hypothermiatranslational medicine

Identifiers

PMID42651842
PMCPMC13510509

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.