CCR5/CCR6 Chemokine Receptor Profiles Differ in γδTCR Intensity-Defined Subsets but Remain Conserved Across Conventional and NK-like γδT Cells During Healthy First-Trimester Pregnancy.

Banan Alrawashdeh, Pál Jáksó, Barbara Forró, Ákos Várnagy, Alíz Barakonyi

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed

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1 · What the graph read from it

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2 · The registry

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5 · Who and what money

Authors and funding

5 authors.

Banan AlrawashdehDepartment of Medical Microbiology, University of Pécs Medical School, Clinical Center, H-7624 Pécs, Hungary.

Pál JáksóDepartment of Pathology, University of Pécs Medical School, Clinical Center, H-7624 Pécs, Hungary.ORCID 0000-0002-5986-3236

Barbara ForróDepartment of Pathology, University of Pécs Medical School, Clinical Center, H-7624 Pécs, Hungary.ORCID 0009-0003-0374-9658

Ákos VárnagyDepartment of Obstetrics and Gynaecology, University of Pécs Medical School, Clinical Center, H-7624 Pécs, Hungary.ORCID 0000-0003-0756-5584

Alíz BarakonyiDepartment of Medical Microbiology, University of Pécs Medical School, Clinical Center, H-7624 Pécs, Hungary.ORCID 0000-0001-5992-4812

Funding

University of Pécs (National Laboratory on Human Reproduction) RRF-2.3.1-21-2022-00012University of Pécs (PTE ÁOK KA ) KA-2025-02

6 · The paper itself

Abstract

During pregnancy, immune tolerance toward the semi-allogeneic fetus must be established. γδT cells constitute a distinct T-cell lineage characterized by expression of the γδT-cell receptor (γδTCR). They combine rapid innate-like responses with adaptive immune functions and contribute to feto-maternal immune regulation; however, their peripheral phenotypic characteristics, including chemokine receptor (ChR) profiles potentially relevant to decidual recruitment, remain incompletely characterized. Peripheral blood from healthy non-pregnant and first-trimester pregnant women was analyzed by flow cytometry to assess γδT-cell phenotypes and CCR5/CCR6 ChR expression. Analysis of γδT-cell subsets defined by lower (γδTCR

Indexed as

CCR5/CCR6 co-expressionCD4/CD8 phenotypechemokine receptorsfirst-trimester pregnancyNK-like γδT cellsperipheral bloodγδT cells

Identifiers

PMID42651690

DOI10.3390/biology15161386

PMCPMC13509355

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.