Cross-Species Conservation and Function of ALDH6A1/Aldh6a1 Validate Zebrafish and Mouse as Complementary Experimental Systems for Methylmalonate Semialdehyde Dehydrogenase Deficiency.

Yanping Zhang, Xiaoqiao Yue, Qiuhong Xiong, Ping Li, Changxin Wu

Abstract read

In one paragraph

Article in Biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yanping ZhangKey Laboratory of Molecular Cell Medicine of Shanxi Province, Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.

Xiaoqiao YueShanxi Bethune Hospital (Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital), Taiyuan 030032, China.

Qiuhong XiongKey Laboratory of Molecular Cell Medicine of Shanxi Province, Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.

Ping LiKey Laboratory of Molecular Cell Medicine of Shanxi Province, Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.ORCID 0000-0002-6137-6154

Changxin WuKey Laboratory of Molecular Cell Medicine of Shanxi Province, Institutes of Biomedical Sciences, Shanxi University, Taiyuan 030006, China.ORCID 0000-0002-7416-1662

Funding

Central Guidance on Local Science and Technology Development Fund of Shanxi Province YDZJSX2021B001The Research Project Supported by Shanxi Scholarship Council of China 2023-007

6 · The paper itself

Abstract

Methylmalonate semialdehyde dehydrogenase deficiency (MMSDD; OMIM #614265) is an ultra-rare autosomal recessive metabolic disorder caused by mutations in the

Indexed as

ALDH6A1/Aldh6a1evolutionary conservationMMSDDmousespatiotemporal expressionzebrafish

Identifiers

PMID42651650

DOI10.3390/biology15161345

PMCPMC13509631

What OpenQuestion holds

Textmetadata

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.