Evidence map›Paper›PMID 42651167›Full record

ArticleBrain sciences2026

Fatigue Induced by Walking Uphill and Downhill Similarly Disrupts Postural Balance but Their Disruptive Factors Differ.

Thierry Paillard, Aurélien Speller, Alex Rizzato, Giuseppe Marcolin, Julien Maitre

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Article in Brain sciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Thierry PaillardLaboratoire Mouvement, Equilibre, Performance et Santé (UR 4445), Université de Pau & Pays de l'Adour, 11 rue Morane Saulnier, 65000 Tarbes, France.ORCID 0000-0002-6492-3889
Aurélien SpellerLaboratoire Mouvement, Equilibre, Performance et Santé (UR 4445), Université de Pau & Pays de l'Adour, 11 rue Morane Saulnier, 65000 Tarbes, France.
Alex RizzatoDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.
Giuseppe MarcolinDepartment of Biomedical Sciences, University of Padova, 35122 Padova, Italy.ORCID 0000-0002-2768-3257
Julien MaitreLaboratoire Mouvement, Equilibre, Performance et Santé (UR 4445), Université de Pau & Pays de l'Adour, 11 rue Morane Saulnier, 65000 Tarbes, France.ORCID 0000-0001-9630-0240

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectivesWalking-induced fatigue disrupts postural balance, but the differentiated effects of walking uphill and downhill remain unclear. The aim was to compare the impact of two walking sequences, either uphill (+10%) or downhill (-20%), with an identical number of steps (7000 steps) on a treadmill at 5.5 km·h

methodsNineteen healthy young participants performed the two walking sequence sessions (56 and 57 min) eight days apart. Eyes-closed bipedal postural balance (in three randomized conditions: an unmanipulated condition, a tendon vibration manipulation condition-TV-and a galvanic vestibular stimulation manipulation condition-GVS), maximal voluntary contraction and central activation ratio were assessed before (PRE), immediately after (POST) and 20 min after (POST20) each walking sequence.

resultsWalking uphill and walking downhill sequences generated similar muscular and central fatigue in the POST and POST20 conditions. In the unmanipulated postural condition, postural balance was disrupted after both walking sequences in the POST condition, with no difference between walking downhill and walking uphill. In the manipulated postural conditions, postural balance was modified by the walking sequences. It was disrupted in the presence of GVS in the POST condition with no difference between walking downhill and uphill, whereas it was not disrupted in the presence of TV and was even improved after walking uphill.

conclusionsAlthough the postural alteration was broadly similar between the two walking sequences, their disruptive factors would differ at the muscular, metabolic and sensory levels.

Indexed as

fatiguepostural controlpostureproprioceptionvestibular inputswalking downhillwalking uphill

Identifiers

PMID42651167
PMCPMC13511059

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.