Evidence map›Paper›PMID 42650965›Full record

ArticleDiagnostics (Basel, Switzerland)2026

Early First-Trimester Diagnosis of Thoracopagus Conjoined Twins with a Shared Cardiac Structure.

Adelina Staicu, Camelia Albu, Roxana Constantin, Iulian Gabriel Goidescu, Mihai Surcel, Dan Boitor-Borza, Andreea Florian, Georgiana Irina Nemeti, Gheorghe Cruciat, Daniel Muresan and 1 more

Abstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adelina Staicu1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.ORCID 0000-0003-3755-320X
Camelia AlbuCentre of Advanced Research Studies, Emergency County Hospital "IMOGEN", 400006 Cluj-Napoca, Romania.ORCID 0000-0001-7224-9778
Roxana Constantin1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Iulian Gabriel Goidescu1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Mihai Surcel1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Dan Boitor-Borza1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-6832-9898
Andreea Florian1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Georgiana Irina Nemeti1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.
Gheorghe Cruciat1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-8162-4103
Daniel Muresan1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-7744-0501
Ioana Cristina Rotar1st Department of Obstetrics and Gynecology, "Iuliu Haţieganu" University of Medicine and Pharmacy Cluj-Napoca, 400012 Cluj-Napoca, Romania.ORCID 0000-0002-7700-2384

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thoracopagus conjoined twins are the most common type of conjoined twinning and are frequently associated with shared cardiac anatomy, the principal determinant of prognosis and postnatal survival. Early prenatal diagnosis is essential for accurate counseling and timely pregnancy management. We report the diagnosis of thoracopagus conjoined twins with a shared cardiac structure in a 35-year-old primigravid woman at 8 weeks and 3 days of gestation. High-resolution transvaginal ultrasound demonstrated persistent thoracic fusion, fixed relative fetal position, a single yolk sac, a single umbilical cord, and absence of an intertwin membrane. Color Doppler confirmed a single sonographically detectable cardiac complex, while three-dimensional ultrasound enhanced spatial visualization and facilitated parental counseling. Differential diagnoses, including monochorionic twins with close apposition, TRAP sequence, body stalk anomaly, and other forms of conjoined twinning, were systematically excluded. Early first-trimester recognition of thoracopagus conjoined twins with shared cardiac anatomy is feasible using dynamic ultrasound and Doppler imaging. Establishing the diagnosis before the end of the first trimester enables accurate prognostic assessment, timely multidisciplinary counseling, and informed parental decision-making for this condition associated with an extremely poor prognosis.

Indexed as

color Dopplerfirst-trimester ultrasoundprenatal diagnosisshared heartthoracopagus conjoined twins

Identifiers

PMID42650965
PMCPMC13511805

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.