Evidence map›Paper›PMID 42650912›Full record

ReviewDiagnostics (Basel, Switzerland)2026

Lumbar Plexus Disorders Presenting as Low Back Pain: A Narrative Review of a Practical Diagnostic Imaging Approach.

Federico Bruno, Raffaele Natella, Giorgio Reverchon, Giulia Pacella, Michela Bruno, Mario Brunese, Giulio Lombardi, Corrado Caiazzo, Marcello Zappia

Abstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Federico BrunoDepartment of Biotechnological and Applied Clinical Sciences, University of L'Aquila, 67100 L'Aquila, Italy.ORCID 0000-0002-1444-2585
Raffaele NatellaDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 84100 Campobasso, Italy.ORCID 0000-0002-5093-8692
Giorgio ReverchonDepartment of Radiology, "St. Giuseppe Moscati" Hospital of National Relevance and High Specialty, 83100 Avellino, Italy.
Giulia PacellaDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 84100 Campobasso, Italy.
Michela BrunoDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 84100 Campobasso, Italy.ORCID 0009-0000-4024-1309
Mario BruneseDepartment of Precision Medicine, University of Campania "L.Vanvitelli", 80138 Napoli, Italy.
Giulio LombardiDepartment of Radiology, "St. Giuseppe Moscati" Hospital of National Relevance and High Specialty, 83100 Avellino, Italy.
Corrado CaiazzoDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 84100 Campobasso, Italy.ORCID 0000-0002-3584-2692
Marcello ZappiaDepartment of Medicine and Health Science "V. Tiberio", University of Molise, 84100 Campobasso, Italy.ORCID 0000-0002-4867-5344

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low back pain (LBP) is one of the most common causes of medical consultation worldwide and is typically attributed to degenerative spinal disorders. However, a subset of patients presents with LBP related to extra-spinal conditions, including disorders of the lumbar plexus. These conditions are often underrecognized and may mimic lumbar radiculopathy, leading to delayed diagnosis or inappropriate management. The lumbar plexus, formed by the anterior rami of L1-L4 nerve roots, lies deep within the psoas muscle and can be affected by a wide range of pathological processes, including traumatic, compressive, inflammatory, infectious, and neoplastic conditions. A targeted literature search of the PubMed/MEDLINE database was performed to identify relevant English-language articles on lumbar plexus disorders, their imaging features, and diagnostic strategies published from inception to June 2026; representative imaging examples were selected from the co-authors' clinical archives. The review summarizes the relevant anatomy, clinical presentation, and key imaging features of the most common plexus pathologies, including retroperitoneal tumors, psoas hematomas, inflammatory plexopathies, and iatrogenic injuries. Advances in imaging techniques, particularly magnetic resonance imaging (MRI) and magnetic resonance neurography (MRN), have significantly improved the ability to visualize the lumbar plexus and detect pathological changes involving peripheral nerves and surrounding structures. Additionally, a practical diagnostic imaging approach is proposed to assist radiologists and clinicians in recognizing lumbar plexus involvement in patients with atypical low back pain.

Indexed as

diabetic amyotrophydiagnostic approachlow back painlumbar plexopathylumbar plexusmagnetic resonance neurographyMRInerve imagingpsoas hematomaretroperitoneal tumors

Identifiers

PMID42650912
PMCPMC13510788

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.