ArticleBiomolecules2026
Two Faces of the Right Ventricle in Fabry Cardiomyopathy: Septal-Coupled and Atrial-Coupled Strain Patterns and Their Differential Associations with Enzyme Replacement Therapy.
Kuo-Tzu Sung, Dau-Ming Niu, Shu-Fen Hsu, Ming-En Liu, Po-Lin Lin, Yau-Huei Lai, Hsiang-Wei Yang, Yung-Hsiu Lu, Cheng-Ting Tsai, Ta-Chuan Hung and 2 more
Abstract read
In one paragraphArticle in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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5 · Who and what moneyAuthors and funding
12 authors.
Kuo-Tzu SungInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0001-7032-9731 Dau-Ming NiuInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.ORCID 0000-0003-3962-1739 Shu-Fen HsuTelehealth Center, MacKay Memorial Hospital, Taipei 104217, Taiwan.
Ming-En LiuDepartment of Medicine, MacKay Medical University, New Taipei City 252005, Taiwan.
Po-Lin LinDepartment of Medicine, MacKay Medical University, New Taipei City 252005, Taiwan.
Hsiang-Wei YangDivision of Cardiology, Hsinchu MacKay Memorial Hospital, Hsinchu 30071, Taiwan.
Yung-Hsiu LuDepartment of Pediatrics, Taipei Veterans General Hospital, Taipei 112201, Taiwan.
Cheng-Ting TsaiDivision of Cardiology, MacKay Memorial Hospital, Taipei 104217, Taiwan.
Ta-Chuan HungDivision of Cardiology, MacKay Memorial Hospital, Taipei 104217, Taiwan.
Po-Sheng ChenDivision of Cardiology, National Cheng Kung University Hospital, Tainan 704302, Taiwan.
Funding
Cognate microglia-neuron interaction and its role in inflammationDP2MH100012 · NIMH · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI SCHAEFER, ANNE · 2012 to 2012
$2.5MNeurocognitive Mechanisms of the Executive Control of Memory and EmotionF31MH110114 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WESTPHAL, ANDREW J · 2016 to 2016
$35kMackay Memorial Hospital 108DMH0100012, 109DMH0100015,10271, 10248, 10220, 10253, 10375, 10358, E-102003, MMH-108-127, MMH-110-114, MMH-110-03, and MMH-D-114-02Ministry of Science and Technology (MOST) (103-2314-B-195-006-MY3, 106-2314-B-195-008-MY2, 108-2314-B-195-018-MY2, 109-2314-B-715-008, 110-2314-B-715-009-MY1, 112-2314-B-715-008-MY3)National Science and Technology Council 101-2314-B-195-020, 103-2314-B-010-005-MY3, 103-2314-B-195-001-MY3, 101-2314-B-195-020-MY1NIMH NIH HHS DP2 MH100012NIMH NIH HHS F31 MH110114NIMH NIH HHS L30 MH108127
6 · The paper itselfAbstract
Right ventricular global longitudinal strain (RVGLS) and right ventricular free-wall longitudinal strain (RVFWLS) are both used to assess right ventricular involvement, but they include different myocardial components. We examined their cross-sectional correlates and longitudinal changes associated with enzyme replacement therapy (ERT) in 100 patients with genetically confirmed Fabry disease, including 69 with serial echocardiography. RVGLS was independently associated with left ventricular global longitudinal strain (LVGLS; standardized β = 0.466,
Indexed as
CardiomyopathiesEnzyme Replacement TherapyFabry DiseaseHeart VentriclesAdultCross-Sectional StudiesEchocardiographyFemaleGlobal Longitudinal StrainHeart AtriaHumansMaleMiddle Agedartificial intelligenceatrial remodelingautomated strain analysisenzyme replacement therapyFabry diseaseright ventricular strain
Identifiers
PMID42650862
PMCPMC13510769
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