ArticleBiomolecules2026
Repurposing of Clomiphene Citrate and Its Antileishmanial and Antifungal Activities:
Leandro Josuel da Costa Santos, Érika de Araújo Abi-Chacra, Rita de Cássia Vianna de Carvalho, Lucas Malaquias França, Denise Andrade do Nascimento, Fernando Aécio de Amorim Carvalho, Gabriel Zazeri, André Luis Menezes Carvalho
Abstract read
In one paragraphArticle in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
8 authors.
Leandro Josuel da Costa SantosPostgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.ORCID 0000-0001-6051-2540 Érika de Araújo Abi-ChacraDepartment of Parasitology and Microbiology, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.
Rita de Cássia Vianna de CarvalhoPostgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.
Lucas Malaquias FrançaUndergraduate Course in Pharmacy, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.
Denise Andrade do NascimentoDepartment of Physics, Federal University of Roraima (UFRR), Boa Vista 69310-000, RR, Brazil.
Fernando Aécio de Amorim CarvalhoPostgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.
Gabriel ZazeriDepartment of Physics, Federal University of Roraima (UFRR), Boa Vista 69310-000, RR, Brazil.ORCID 0000-0001-9957-9697 André Luis Menezes CarvalhoPostgraduate Program in Pharmaceutical Sciences, Federal University of Piauí, Campus Ministro Petrônio Portela, Teresina 64049-550, PI, Brazil.
Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico 01.24.0609.00-Ref.: 2382/24Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.805628/2023-00
6 · The paper itselfAbstract
This study investigated the repurposing potential of clomiphene citrate as a topical therapeutic candidate for tegumentary leishmaniasis (TL) and candidiasis. Comparative
Indexed as
Antifungal AgentsAntiprotozoal AgentsClomipheneDrug RepositioningAnimalsBiofilmsCandida albicansComputer SimulationHumansLeishmaniaMicrobial Sensitivity TestsMolecular Docking SimulationAntifungal AgentsAntiprotozoal AgentsClomipheneADMECandida albicansclomiphenecutaneous leishmaniasisdrug repurposingin silico study
Identifiers
PMID42650801
PMCPMC13511042
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