Evidence map›Paper›PMID 42650760›Full record

ArticleBiomolecules2026

Unraveling Effects and Pharmacological Mechanisms of Phellodendrine on Inflammatory Bowel Disease.

Yufeng Xie, Ziyi Zhou, Xuqianzi Wu, Jiayin Teng, Xiaorun Zhang, Yue Sun, Lixin Chen, Lijian Ding, Wei Yuan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yufeng XieJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Ziyi ZhouJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Xuqianzi WuJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Jiayin TengJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Xiaorun ZhangJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Yue SunJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Lixin ChenJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.
Lijian DingSchool of Pharmacy, Health Science Center, Ningbo University, Ningbo 315211, China.ORCID 0000-0002-2259-9830
Wei YuanJiangxi Provincial Key Laboratory of Synthetic Pharmaceutical Chemistry, School of Geography and Environmental Engineering, Gannan Normal University, Ganzhou 341000, China.

Funding

Degree and Graduate Education Reform Research Project of Gannan Normal University YJG-2023-06Educational Commission of Hubei Province of China Q20231610Gannan Normal University Training Program of Innovation and Entrepreneurship for Undergraduates CX220078Gannan Normal University Training Program of Innovation and Entrepreneurship for Undergraduates CX230078Gannan Normal University Training Program of Innovation and Entrepreneurship for Undergraduates CX240100Gannan Normal University Training Program of Innovation and Entrepreneurship for Undergraduates CX240113Natural Science Foundation Project of Jiangxi Province 20212BAB215001Ningbo youth science and technology innovation leading project 2024QL063Research Project of Wuhan Polytechnic University 2022Y14Special Fundfor Graduate Student Innovation Gannan Normal University YCXJ25-B23
6 · The paper itself

Abstract

Inflammatory bowel disease (IBD) is characterized by chronic inflammation of the gastrointestinal tract. Current treatments, including anti-inflammatory drugs and biologics, often have limited efficacy and significant side effects, highlighting the need for novel therapeutic approaches. Phellodendrine (PHE) is a characteristic ingredient of

Indexed as

Anti-Inflammatory AgentsInflammatory Bowel DiseasesAnimalsDextran SulfateDisease Models, AnimalGastrointestinal MicrobiomeInflammationIntestinal Barrier FunctionOxidative StressQuinolizinesZebrafishAnti-Inflammatory AgentsDextran SulfatephellodendrineQuinolizinesanti-inflammationgut microbiotainflammatory bowel diseaseintestinal barrieroxidative stressPhellodendrine

Identifiers

PMID42650760
PMCPMC13510209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.