Evidence map›Paper›PMID 42650749›Full record

ArticleBiomolecules2026

Human Neutrophils Produce De Novo Thyroid Hormones Mediated by the Induction of the Oxidative Burst.

Mahmood Y Bilal, Umida Ganieva, Thanh Luu, Joanne Kwak-Kim, Svetlana Dambaeva

Abstract read
In one paragraph

Article in Biomolecules, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mahmood Y BilalClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
Umida GanievaClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.ORCID 0000-0001-9890-8946
Thanh LuuCenter for Cancer Cell Biology, Immunology, and Infection, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.
Joanne Kwak-KimCenter for Cancer Cell Biology, Immunology, and Infection, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.ORCID 0000-0002-8409-1645
Svetlana DambaevaClinical Immunology Laboratory, Rosalind Franklin University of Medicine and Science, North Chicago, IL 60064, USA.ORCID 0000-0002-1145-1814

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thyroid hormone synthesis involves several key steps culminating in the organification of iodide into iodothyronines, thyroxine, and triiodothyronine. To date, there is no clear mechanistic evidence of extrathyroidal iodothyronine synthesis. Upon iodine (KI/I

Indexed as

NeutrophilsRespiratory BurstThyroid HormonesHumansHydrogen PeroxideNADPH OxidasesPeroxidaseThyroglobulinHydrogen PeroxideNADPH OxidasesPeroxidaseThyroglobulinThyroid Hormonesextrathyroidal thyroxineiodineMPOneutrophil iodinationoxidative burst

Identifiers

PMID42650749
PMCPMC13511619

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.