ArticleChildren (Basel, Switzerland)2026
Early Enzyme-Alginogel Treatment Improves Healing and Reduces Complications, Scarring, and Healthcare Burden in Children with Mild-to-Moderate Burns: A Retrospective Real-World Study.
Article in Children (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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12 authors.
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Abstract
BACKGROUND/
objectivesPediatric mild-to-moderate burns require careful management in the early phase, yet evidence guiding optimal initial dressing selection remains limited. Although topical medications and specialized dressings are routinely used, a universally accepted standard of care is lacking.
methodsWe conducted a 1-year, real-world, retrospective, comparative, single-center study evaluating whether treatment with enzyme alginogel (Flaminal
resultsDespite a higher proportion of deep burns, early treatment with enzyme alginogel was associated with a 6.17-day [95% Confidence Interval: 4.71-7.63 days] shorter healing time (
conclusionsEarly management with alginogel favored healing, reduced complications, improved scar outcomes, and reduced burden of care in comparison to the initial treatment with NaOCl-based antiseptic dressings followed by treatment change when clinically indicated. Prospective, comparative, randomized studies are needed to confirm these findings.
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