Evidence map›Paper›PMID 42650179›Full record

ReviewAntioxidants (Basel, Switzerland)2026

Alpha-Mangostin in Acute Kidney Injury: Molecular Mechanisms, Regulated Cell Death, and Translational Opportunities.

Atthaphong Phongphithakchai, Nawanwat C Pattaranggoon, Kraiyasak Wongna, Ratana Netphakdee, Aman Tedasen, Chutima Jansakun, Wiyada Kwanhian Klangbud, Jongkonnee Thanasai, Fumitaka Kawakami, Moragot Chatatikun

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antioxidants (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Atthaphong PhongphithakchaiNephrology Unit, Division of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand.ORCID 0000-0001-8422-2644
Nawanwat C PattaranggoonSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0000-0001-8706-8881
Kraiyasak WongnaSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Ratana NetphakdeeSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0009-0009-5418-8540
Aman TedasenSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.
Chutima JansakunSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0000-0002-7892-4436
Wiyada Kwanhian KlangbudMedical Technology Program, Faculty of Science, Nakhon Phanom University, Nakhon Phanom 48000, Thailand.ORCID 0000-0002-5247-166X
Jongkonnee ThanasaiFaculty of Medicine, Mahasarakham University, Mahasarakham 44000, Thailand.ORCID 0009-0004-4542-8980
Fumitaka KawakamiDepartment of Regulation Biochemistry, Graduate School of Medical Sciences, Kitasato University, Sagamihara 252-0373, Japan.ORCID 0000-0002-8781-2516
Moragot ChatatikunSchool of Allied Health Sciences, Walailak University, Nakhon Si Thammarat 80160, Thailand.ORCID 0000-0003-3264-1155

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute kidney injury (AKI) is a major global health challenge associated with substantial morbidity, mortality, and progression to chronic kidney disease. Increasing evidence indicates that oxidative stress, mitochondrial dysfunction, inflammatory signaling, regulated cell death, and maladaptive tissue repair play central roles in AKI pathogenesis, yet effective disease-modifying pharmacological therapies remain unavailable. This narrative review critically evaluated current evidence regarding the pharmacological characteristics, molecular mechanisms, and translational potential of alpha-mangostin (AM), the principal prenylated xanthone isolated from the pericarp of

Indexed as

acute kidney injuryalpha-mangostinapoptosisinflammationmitochondriaoxidative stresstranslational medicine

Identifiers

PMID42650179
PMCPMC13509643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.