Evidence map›Paper›PMID 42650084›Full record

ArticleGenes2026

Integrated Transcriptomic and Metabolomic Analyses Reveal Early Concentration-Dependent Responses of

Dabao Yin, Xue Li, Li Zhou, Zhongchun Xiao

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dabao YinQianxinan Collaborative Innovation Center for Characteristic Industrial Poverty Alleviation and Ecological Restoration, College of Biology and Chemistry, Minzu Normal University of Xingyi, Xingyi 562400, China.
Xue LiQianxinan Collaborative Innovation Center for Characteristic Industrial Poverty Alleviation and Ecological Restoration, College of Biology and Chemistry, Minzu Normal University of Xingyi, Xingyi 562400, China.
Li ZhouQianxinan Collaborative Innovation Center for Characteristic Industrial Poverty Alleviation and Ecological Restoration, College of Biology and Chemistry, Minzu Normal University of Xingyi, Xingyi 562400, China.
Zhongchun XiaoQianxinan Collaborative Innovation Center for Characteristic Industrial Poverty Alleviation and Ecological Restoration, College of Biology and Chemistry, Minzu Normal University of Xingyi, Xingyi 562400, China.

Funding

Doctoral Research Startup Fund of Minzu Normal University of Xingyi: Study on the Molecular Mechanism of Differences in Pericarp Color, Active Ingredient Content and Yield of Glycyrrhiza uralensis 24XYBS34Guizhou Provincial Department of Education University Science and Technology Innovation Team Project (2023) 095Qianxinan Collaborative Innovation Center for Characteristic Industrial Poverty Alleviation and Ecological Restoration 26XYPT06
6 · The paper itself

Abstract

backgroundImidacloprid, a widely used neonicotinoid insecticide, is routinely applied to control pests in

methodsIn this study, 80-day seedlings were subjected to three foliar spray treatments: blank control (CK), the recommended imidacloprid concentration (2000-fold dilution, 475 mg·L

resultsThe low- and high-dose treatments induced 1076 and 860 differential metabolites and 6818 and 7283 differentially expressed genes, respectively. Flavonoids, saponins, terpenoids, amino acid metabolites, and energy-related pathways were prominently affected. KEGG enrichment indicated activation of flavone/flavonol biosynthesis, phenylpropanoid metabolism, amino acid metabolism, MAPK signaling, cutin/suberin/wax biosynthesis, and ABC transporter pathways, whereas high-dose exposure was associated with stronger changes in genes related to DNA replication and cell wall remodeling. Integrated network analysis highlighted

conclusionsSeedlings of

Indexed as

Astragalus propinquusInsecticidesMetabolomeNeonicotinoidsNitro CompoundsSeedlingsTranscriptomeGene Expression ProfilingGene Expression Regulation, PlantMetabolomicsimidaclopridInsecticidesNeonicotinoidsNitro CompoundsAstragalus membranaceus var. mongholicusimidaclopridmetabolomicstranscriptomics

Identifiers

PMID42650084
PMCPMC13512319

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.