Evidence map›Paper›PMID 42650065›Full record

ReviewGenes2026

Advances in Research on

Zhenyu Yang, Wendiao Zhang, Fengyi Yu, Xiaomei Duan, Miaojin Zhou, Beisha Tang

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zhenyu YangDepartment of Neurology, Multi-Omics Research Center for Brain Disorders, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.ORCID 0009-0003-9081-1869
Wendiao ZhangDepartment of Neurology, Multi-Omics Research Center for Brain Disorders, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.ORCID 0000-0002-3510-8383
Fengyi YuHengyang Medical School, University of South China, Hengyang 421001, China.
Xiaomei DuanDepartment of Neurology, Multi-Omics Research Center for Brain Disorders, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.
Miaojin ZhouHengyang Medical School, University of South China, Hengyang 421001, China.ORCID 0000-0002-6636-6000
Beisha TangDepartment of Neurology, Multi-Omics Research Center for Brain Disorders, The First Affiliated Hospital, Hengyang Medical School, University of South China, Hengyang 421001, China.

Funding

China Postdoctoral Science Foundation 2024M761362National Natural Science Foundation of China 82394421National Natural Science Foundation of China 82401768National Postdoctoral Program for Innovative Talent BX20240155Natural Science Foundation of Hunan Province 2025JJ90133
6 · The paper itself

Abstract

Leukodystrophies (LDs), a group of heterogeneous genetic disorders, are characterized by selective involvement of cerebral white matter, including abnormal white matter development and/or progressive degeneration. Oligodendrocytes, astrocytes, microglia, axons, and the neurovascular unit collectively contribute to white matter homeostasis and disease progression. Recently, genomic sequencing has identified pathogenic variants in the alanyl-tRNA synthetase 1 (

Indexed as

Alanine-tRNA LigaseAmino Acyl-tRNA SynthetasesHereditary Central Nervous System Demyelinating DiseasesAnimalsHumansMitochondriaAARS2 protein, humanAlanine-tRNA LigaseAmino Acyl-tRNA SynthetasesAARS1AARS2alanyl tRNA synthetaseleukodystrophies

Identifiers

PMID42650065
PMCPMC13512900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.