Evidence map›Paper›PMID 42650050›Full record

ArticleGenes2026

Genome-Wide Identification of a Chromatin-Splicing Regulatory Axis Driven by DOT1L in MLL-Rearranged Acute Myeloid Leukemia.

Qi Liu, Bowen Yang, Tianbao Li, Raven Garcia, Shengtong Han, Victor X Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Qi LiuDepartment of Bioinformatics, Drylab Inc., Quincy, MA 02171, USA.
Bowen YangDepartment of Diagnostic and Interventional Imaging, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.ORCID 0000-0002-5272-8349
Tianbao LiDepartment of Bioinformatics, Drylab Inc., Quincy, MA 02171, USA.
Raven GarciaDepartment of Molecular Medicine, UT Health San Antonio, San Antonio, TX 78229, USA.
Shengtong HanSchool of Dentistry, Marquette University, Milwaukee, WI 53233, USA.ORCID 0000-0002-7203-1143
Victor X JinData Science Institute, Medical College of Wisconsin, Milwaukee, WI 53226, USA.ORCID 0000-0002-8765-3471

Funding

Omics analysis of three-dimensional transcriptional regulationR01GM114142 · NIGMS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI JIN, VICTOR, LIN, SHILI · 2015 to 2024
$2.7M
NIGMS NIH HHS R01 GM114142
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ChromatinHistone-Lysine N-MethyltransferaseLeukemia, Myeloid, AcuteMyeloid-Lymphoid Leukemia ProteinAlternative SplicingBenzimidazolesCell Line, TumorExonsGene RearrangementHistonesHumansBenzimidazolesChromatinDOT1L protein, humanEPZ-5676Histone-Lysine N-MethyltransferaseHistonesKMT2A protein, humanMyeloid-Lymphoid Leukemia Proteinacute myeloid leukemiaalternative splicingDOT1Lepigenetic regulationexon skippingH3K79 methylationMLL rearrangementRNA processing

Identifiers

PMID42650050
PMCPMC13512208

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.