Evidence map›Paper›PMID 42649779›Full record

ArticleBioengineering (Basel, Switzerland)2026

Clinical Performance of Infrazygomatic Crest Miniscrews Placed Without Surgical Guides: A Retrospective Study with 30-Month Follow-Up.

Gianna Dipalma, Alessio Danilo Inchingolo, Maral Di Giulio Cesare, Sharon Di Serio, Marialuisa Longo, Francesco Inchingolo, Marco Severino, Ioana Roxana Bordea, Grazia Marinelli, Angelo Michele Inchingolo

Abstract read
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Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Gianna DipalmaInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Alessio Danilo InchingoloInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-6366-1039
Maral Di Giulio CesareInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Sharon Di SerioInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Marialuisa LongoInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Francesco InchingoloInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-3797-5883
Marco SeverinoDepartment of Medicine and Surgery, University of Perugia, Severi Square n.1, 06132 Perugia, Italy.ORCID 0000-0003-3518-130X
Ioana Roxana BordeaDepartment of Oral Rehabilitation, Faculty of Dentistry, Iuliu Hatiegan University of Medicine and Pharmacy, 400012 Cluj-Napoca, Romania.ORCID 0000-0001-7166-9949
Grazia MarinelliInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0001-9163-2350
Angelo Michele InchingoloInterdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-0104-6337

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfrazygomatic crest (IZC) miniscrews provide reliable extra-alveolar skeletal anchorage for orthodontic tooth movement while minimizing dependence on patient compliance. Although guided insertion techniques have been proposed to improve placement accuracy, freehand insertion remains widely used because of its simplicity and clinical practicality. This retrospective study evaluated the clinical performance and survival of freehand-placed IZC miniscrews over a minimum follow-up period of 30 months. MATERIALS AND

methodsA retrospective observational study was conducted on 23 consecutive patients receiving a total of 30 IZC miniscrews between January 2022 and July 2024. All miniscrews were placed freehand by the same experienced orthodontist following individualized radiographic planning based on panoramic radiography and/or cone-beam computed tomography (CBCT), according to the patient's anatomical requirements. Miniscrews were immediately loaded using light orthodontic forces (<100 g), with progressive force increases during subsequent appointments based on treatment objectives. Patients were reviewed at approximately 30-35-day intervals. Clinical records were analyzed to assess miniscrew survival, timing of failure, and procedure-related complications using descriptive statistical analysis.

resultsTwenty-seven of the 30 miniscrews remained clinically stable throughout treatment, corresponding to an overall success rate of 90.0%. Three failures occurred during the early treatment phase, while no late failures were observed. Because of the limited number of failure events, potential contributing factors-including screw dimensions, mechanical interference, and deterioration of oral hygiene during treatment-were evaluated descriptively and should be interpreted with caution. No major surgical or radiographic complications were detected during follow-up.

conclusionsWithin the limitations of this retrospective observational study, freehand placement of IZC miniscrews demonstrated favorable clinical performance when performed by an experienced operator following appropriate radiographic planning. However, the relatively small sample size, absence of a control group, and descriptive nature of the analysis preclude definitive conclusions regarding factors influencing miniscrew failure or the comparative effectiveness of freehand versus guided insertion. Larger prospective controlled studies are warranted to validate these preliminary findings. Clinical relevance Manual IZC miniscrew insertion represents a predictable, efficient, and cost-effective alternative to guided approaches in orthodontic practice.

Indexed as

bone screwsmalocclusionmaxillaorthodontic anchorage proceduresretrospective studieszygoma

Identifiers

PMID42649779
PMCPMC13509864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.