Evidence map›Paper›PMID 42649754›Full record

ArticleBioengineering (Basel, Switzerland)2026

Tooth Color Change Following Bleaching with a Desensitizing Double-Layer Technique.

Basil Almutairi, Abdullah Alshehri, Hamad Algamaiah, Carlos A Jurado, Silvia Rojas-Rueda, Muadh A AlGomaiah, Abdulrahman Alshabib

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Basil AlmutairiDepartment of Restorative Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.ORCID 0009-0007-1604-1332
Abdullah AlshehriConservative Dental Science Department, College of Dentistry, Prince Sattam Bin Abdulaziz University, Al-Kharj, Riyadh 16245, Saudi Arabia.
Hamad AlgamaiahDepartment of Restorative Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.
Carlos A JuradoSchool of Dental Medicine, Ponce Health Sciences University, Ponce, PR 00732, USA.ORCID 0000-0001-7437-4855
Silvia Rojas-RuedaSchool of Dental Medicine, Ponce Health Sciences University, Ponce, PR 00732, USA.ORCID 0009-0003-3245-5245
Muadh A AlGomaiahDepartment of Pediatric Dentistry and Orthodontics, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.ORCID 0009-0009-8011-8503
Abdulrahman AlshabibDepartment of Restorative Dental Science, College of Dentistry, King Saud University, P.O. Box 60169, Riyadh 11545, Saudi Arabia.ORCID 0000-0001-8890-8707

Funding

Prince Sattam Bin Abdulaziz University PSAU/2024/R/1446
6 · The paper itself

Abstract

This in vitro study evaluated the effect of incorporating a desensitizing layer between the tooth surface and bleaching gel on tooth color change and treatment time during in-office bleaching procedures. The novelty of this study lies in assessing whether a double-layer technique, previously proposed to modify the diffusion behavior of potassium nitrate and hydrogen peroxide, can maintain whitening efficacy while reducing overall application time. Sixty caries-free third molars were randomly assigned to three groups (n = 20). The CTRL group received 25% hydrogen peroxide (HP) for 30 and 45 min; the DL group received a double-layer application consisting of 5% potassium nitrate followed by 25% HP for the same time intervals; and the MIXED group received 3% potassium nitrate incorporated into 40% HP. Tooth color was measured with a digital spectrophotometer at the baseline and after each treatment interval. Repeated measures ANOVA and pairwise

Indexed as

color changedouble-layer techniquepotassium nitratetooth bleachingtooth whitening

Identifiers

PMID42649754
PMCPMC13510064

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.