Evidence map›Paper›PMID 42649521›Full record

ArticleTropical medicine and health2026

Molecular identification of Hypoderma sinense cutaneous myiasis in a child from a cattle-raising pastoral region of China: a case report.

Qiuqin Ji, Shuyao He, Sha Lai, Siqi Long, Xinyi Jing, Yao Lu

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Article in Tropical medicine and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Qiuqin Ji *Department of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China.
Shuyao He *Department of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China.
Sha LaiDepartment of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China.
Siqi LongDepartment of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China.
Xinyi JingDepartment of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China.
Yao LuDepartment of Dermatology, Chengdu Women's and Children's Central Hospital, School of Medicine, University of Electronic Science and Technology of China, Riyue Avenue, Chengdu, 611731, China. peapeapea@163.com.ORCID http://orcid.org/0000-0002-8108-6656

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHuman cutaneous myiasis caused by Hypoderma sinense is rarely reported and may be mistaken for common bacterial skin disease. CASE PRESENTATION: A 3-year-old boy from a livestock-raising pastoral region of China presented with multiple painful subcutaneous nodules that had not responded to topical antibacterial treatment. Marked eosinophilia, elevated total IgE, and linear ultrasonographic structures raised suspicion of parasitic infestation. A larva was removed intact from the posterior neck lesion through a pre-existing punctum under local anesthesia. Whole-genome shotgun sequencing followed by de novo assembly generated a 16,888-bp mitochondrial contig containing a complete COI barcode region, supporting identification of the larva as H. sinense. At the one-month follow-up, the pain and subcutaneous nodules had resolved.

conclusionsThis case highlights the importance of considering cutaneous myiasis in children from livestock-raising regions with painful, treatment-resistant subcutaneous nodules and demonstrates the diagnostic value of ultrasonography, minimally invasive larval extraction, and molecular identification.

Indexed as

CattleDNA barcodingHypoderma sinenseMyiasisParasiticSkin diseasesTaxonomicUltrasonographyWhole-genome sequencingZoonoses

Identifiers

PMID42649521
PMCPMC13508318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.