Evidence map›Paper›PMID 42649382›Full record

ArticleNature plants2026

Evolutionary tuning of the molecular charge state of UBP24 shapes responses to high temperature.

Shao-Li Yang, Hongyan Liu, Xiangyu Xu, Anton Gorkovskiy, Monica L Garcia Gomez, Kirsten Ten Tusscher, Jennifer Molinet, Božena Klodová, Tingting Zhu, Cassio Flavio Fonseca De Lima and 8 more

Abstract read
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In one paragraph

Article in Nature plants, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Shao-Li YangDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0003-0989-5448
Hongyan LiuDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Xiangyu XuDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-6492-9770
Anton GorkovskiyKU Leuven, Department of Microbial and Molecular Systems (M²S), Centre of Microbial and Plant Genetics (CMPG), Leuven, Belgium.ORCID http://orcid.org/0000-0003-4811-2282
Monica L Garcia GomezTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands.
Kirsten Ten TusscherTheoretical Biology and Bioinformatics, Utrecht University, Utrecht, the Netherlands.ORCID http://orcid.org/0000-0002-1945-7858
Jennifer MolinetDepartment of Zoology, Stockholm University, Stockholm, Sweden.
Božena KlodováDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Tingting ZhuDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Cassio Flavio Fonseca De LimaDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Brigitte Van De CotteDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Karin VoordeckersKU Leuven, Department of Microbial and Molecular Systems (M²S), Centre of Microbial and Plant Genetics (CMPG), Leuven, Belgium.ORCID http://orcid.org/0000-0001-6397-840X
Toshinori KinoshitaInstitute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Chikusa Nagoya, Japan.ORCID http://orcid.org/0000-0001-7621-1259
Kevin J VerstrepenKU Leuven, Department of Microbial and Molecular Systems (M²S), Centre of Microbial and Plant Genetics (CMPG), Leuven, Belgium.ORCID http://orcid.org/0000-0002-3077-6219
Rike StelkensDepartment of Zoology, Stockholm University, Stockholm, Sweden.
Kris GevaertDepartment of Biomolecular Medicine, Ghent University, Ghent, Belgium.ORCID http://orcid.org/0000-0002-4237-0283
Lam Dai VuDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium.
Ive De SmetDepartment of Plant Biotechnology and Bioinformatics, Ghent University, Ghent, Belgium. ive.desmet@psb.vib-ugent.be.ORCID http://orcid.org/0000-0003-4607-8893

Funding

Bijzonder Onderzoeksfonds (Special Research Fund) 01CD7122Bijzonder Onderzoeksfonds (Special Research Fund) 01P11322China Scholarship Council (CSC) 201706350153China Scholarship Council (CSC) 201706910095China Scholarship Council (CSC) 202204910025Foundation for Food and Agriculture Research (FFAR) KICH3.LTP.20.005
6 · The paper itself

Abstract

Protein evolution is shaped by sequence variation that modulates protein properties-for example, through the gain or loss of post-translational modifications. Among these, reversible phosphorylation alters a protein's overall electrical charge and enables organisms to dynamically respond to environmental fluctuations. In plants, the hydro-active opening of stomata, microscopic pores that regulate gas exchange and leaf temperature, is governed by phosphorylation-dependent signalling. Here we identify a mechanism involving the deubiquitylase UBIQUITIN-SPECIFIC PROTEASE 24 (UBP24) that promotes stomatal opening in Arabidopsis thaliana under heat. UBP24 is phosphorylated at serine 360 by the kinase OPEN STOMATA 1, which is activated by B4 RAF kinases in response to heat stress. This phosphorylation stabilizes UBP24, enabling the deubiquitylation of a plasma membrane H

Indexed as

ArabidopsisArabidopsis ProteinsEvolution, MolecularHot TemperatureUbiquitin-Specific ProteasesPhosphorylationPhosphotransferasesPlant StomataProtein Serine-Threonine KinasesSignal TransductionArabidopsis ProteinsAt3g51550 protein, ArabidopsisPhosphotransferasesProtein Serine-Threonine KinasesUbiquitin-Specific Proteases

Identifiers

PMID42649382

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.