Evidence map›Paper›PMID 42649362›Full record

ArticleScientific reports2026

UV-protective sunscreen compounds and their differential accumulation across ocular tissues in fish eyes from Baltic Sea.

Ulf Karsten, Laureen Walberg, Uwe Krumme, Friederike Schaub, Oliver Stachs, Karsten Sperlich, Tobias Lindner, Fabian Hammerle, Johanna M Gostner, Cornelia A Karg and 1 more

Abstract read
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In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ulf KarstenDepartment of Applied Ecology and Phycology, Institute of Biological Sciences, University of Rostock, Albert-Einstein-Strasse 3, 18051, Rostock, Germany. ulf.karsten@uni-rostock.de.ORCID 0000-0002-2955-0757
Laureen WalbergDepartment of Applied Ecology and Phycology, Institute of Biological Sciences, University of Rostock, Albert-Einstein-Strasse 3, 18051, Rostock, Germany.
Uwe KrummeThuenen Institute of Baltic Sea Fisheries, Alter Hafen Süd 2, 18069, Rostock, Germany.
Friederike SchaubDepartment of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057, Rostock, Germany.
Oliver StachsDepartment of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057, Rostock, Germany.
Karsten SperlichDepartment of Ophthalmology, Rostock University Medical Center, Doberaner Straße 140, 18057, Rostock, Germany.
Tobias LindnerCore Facility Multimodal Small Animal Imaging, University Medical Center Rostock, 18057, Rostock, Germany.
Fabian HammerleInstitute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Johanna M GostnerInstitute of Medical Biochemistry, Medical University of Innsbruck, 6020, Innsbruck, Austria.
Cornelia A KargInstitute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.
Markus GanzeraInstitute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 80-82, 6020, Innsbruck, Austria.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many fish species achieve ultraviolet radiation (UVR) protection by accumulating mycosporine-like amino acids (MAAs) from their diet. High concentrations are often found in the eyes, but the localization of MAAs in specific fish eye tissues is unknown. In the present study we dissected the eyes of six fish species, and prepared cornea, lens, vitreous body and a mixed tissue sample consisting of retina, choroidea and sclera (RCS). Furthermore, to test if MAAs are transferred further up the food web, we investigated the occurrence of MAAs also in eyes of warm-blooded piscine predators. Most, but not all, fish eye tissue samples contained the MAAs palythine, asterina-330, usujirene and palythene, but in different quantitative patterns. The highest MAA concentrations were found in the cornea, lens and vitreous body, while the innermost RCS layer showed a much smaller content. All data indicate that most MAAs are mainly located in the cornea and/or lens and vitreous body, thereby providing an improved photoprotection of the RCS layer, and in particular of the innermost, UVR-sensitive retina. No MAAs were detected in the eyes of cormorants and piscivorous mammals, suggesting that the trophic transfer of MAAs from the primary producers via zooplankton apparently ends in the fish.

Indexed as

EyeFishesSunscreening AgentsAmino AcidsAnimalsCorneaLens, CrystallineOceans and SeasUltraviolet RaysAmino AcidsSunscreening AgentsDemersal fishesMycosporine-like amino acidsOcular tissuesPiscine predatorsTrophic transferVisual ecology

Identifiers

PMID42649362
PMCPMC13518351

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.