Evidence map›Paper›PMID 42649359›Full record

ArticleScientific reports2026

Impact of combined acidic and oxidative stress on guanine DNA damage.

Islam G Ali, Nada A Khaled, Hanan Elhaes, Medhat A Ibrahim

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Islam G AliPhysics Department, Faculty of Science, Arish University, Arish, 45511, Egypt.
Nada A KhaledTherapeutic Chemistry Department, National Research Centre, 33 El-Bohouth St., Dokki, Giza, 12622, Egypt.
Hanan ElhaesPhysics Department, Faculty of Women for Arts, Science and Education, Ain Shams University, Cairo, 11757, Egypt.
Medhat A IbrahimSpectroscopy Department, National Research Centre, 33 El-Bohouth St., 12622, Dokki, Giza, Egypt. Medhat.AbdElkhalk@bnu.edu.eg.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research investigates guanine reactivity through quantum-chemical methods which study its behaviour during simultaneous oxidative and acidic stress using Density Functional Theory at the B3LYP/6-31G(d, p) computational method. The researchers tested three systems which contained the •OH group addition at C17 (canonical C8) and the H

Indexed as

AcidsDNA DamageGuanineOxidative StressDNAHydrogen BondingModels, MolecularQuantum TheoryStatic ElectricityAcidsDNAGuanineDFTDNA damageGuanineHOMO–LUMOMESP QTAIMNBO and NCI

Identifiers

PMID42649359
PMCPMC13518821

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.