Evidence map›Paper›PMID 42649296›Full record

ArticleNature2026

Long-read sequencing reveals pre-meiotic gene conversion in sperm.

Regev Schweiger, Sangjin Lee, Chenxi Zhou, Tsun-Po Yang, Stacy Li, Rashesh Sanghvi, Matthew Neville, Katie Smith, Kirsty Roberts, Ayrun Nessa and 7 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Regev SchweigerDepartment of Human Genetics and Computational Medicine, Gray School of Medical Sciences, Gray Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.
Sangjin LeeCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-1741-0052
Chenxi ZhouDepartment of Genetics, University of Cambridge, Cambridge, UK.ORCID http://orcid.org/0000-0002-1735-2630
Tsun-Po YangCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.
Stacy LiDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0001-8726-7995
Rashesh SanghviCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-7703-9216
Matthew NevilleCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0001-5816-7936
Katie SmithCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0009-0000-2198-2734
Kirsty RobertsCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.
Ayrun NessaDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Sam WadgeDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.
Kerrin S SmallDepartment of Twin Research and Genetic Epidemiology, King's College London, London, UK.ORCID http://orcid.org/0000-0003-4566-0005
Peter J CampbellCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK.ORCID http://orcid.org/0000-0002-3921-0510
Kristian AlmstrupDepartment of Growth and Reproduction, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-1832-0307
Peter H SudmantDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA, USA.ORCID http://orcid.org/0000-0002-9573-8248
Raheleh RahbariCancer Ageing and Somatic Mutation, Wellcome Sanger Institute, Hinxton, UK. rr11@sanger.ac.uk.ORCID http://orcid.org/0000-0002-1839-7785
Richard DurbinDepartment of Genetics, University of Cambridge, Cambridge, UK. rd109@cam.ac.uk.ORCID http://orcid.org/0000-0002-9130-1006

Funding

Wellcome Trust
6 · The paper itself

Abstract

Meiotic recombination is a fundamental process that generates genetic diversity by creating new combinations of existing alleles

Indexed as

Crossing Over, GeneticGene ConversionMeiosisSequence Analysis, DNASpermatozoaChromosome Fragile SitesDNA Breaks, Double-StrandedHistone-Lysine N-MethyltransferaseHumansMalePedigreeHistone-Lysine N-MethyltransferasePRDM9 protein, human

Identifiers

PMID42649296
PMCPMC13600919

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.