Evidence map›Paper›PMID 42649291›Full record

ArticleNature2026

Aberrant excitatory neuronal ERBB4 promotes Alzheimer's disease pathology.

Se Young Lee, Eunseok Park, Ha-Eun Lee, Seongbin Kim, Yeji Yeo, Juwon Park, Young-Jin Choi, Kiheon Lee, Ki-Jun Yoon, Sanghoon Park and 3 more

Abstract read
PubMed Publisher
In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Se Young LeeCenter for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Eunseok Park *Center for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Ha-Eun Lee *Department of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.
Seongbin KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID http://orcid.org/0009-0000-1105-5558
Yeji YeoDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0002-2946-3514
Juwon ParkCenter for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Young-Jin ChoiCenter for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea.
Kiheon LeeDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Ki-Jun YoonDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0003-2985-2541
Sanghoon ParkIllimis Therapeutics, Seoul, Republic of Korea.
Eunjoon KimDepartment of Biological Sciences, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.ORCID http://orcid.org/0000-0001-5518-6584
Jae-Ick KimDepartment of Biological Sciences, Ulsan National Institute of Science and Technology (UNIST), Ulsan, Republic of Korea.ORCID http://orcid.org/0000-0001-9705-0394
Won-Suk ChungCenter for Vascular Research, Institute for Basic Science (IBS), Daejeon, Republic of Korea. wonsuk.chung@kaist.ac.kr.ORCID http://orcid.org/0000-0003-1060-9007

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation and synapse loss are associated with cognitive decline in Alzheimer's disease (AD). Although microglial hyperphagocytic activity has been implicated in synapse loss

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.