Pyridoxal photoenzymes for asymmetric radical-radical cross-couplings.

Cole C Sorensen, Suhao Wang, Yao Ouyang, Saim Waheed, Claire G Page, Greg Mann, Simon Allmendinger, Todd K Hyster

Abstract read

In one paragraph

Article in Nature, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cole C Sorensen *Department of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-0705-9406

Suhao Wang *Department of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0009-0003-3491-8768

Yao OuyangDepartment of Chemistry, Princeton University, Princeton, NJ, USA.

Saim WaheedDepartment of Chemistry, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-4144-2748

Claire G PageDepartment of Chemistry, Princeton University, Princeton, NJ, USA.

Greg MannNovartis Pharma, Basel, Switzerland.

Simon AllmendingerNovartis Pharma, Basel, Switzerland.ORCID http://orcid.org/0009-0004-7598-083X

Todd K HysterDepartment of Chemistry, Princeton University, Princeton, NJ, USA. thyster@princeton.edu.ORCID http://orcid.org/0000-0003-3560-355X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-native photoenzymes have enabled myriad asymmetric bond-forming events that are otherwise challenging or at present impossible with small-molecule catalysis

Indexed as

Pyridoxal PhosphateCoenzymesFree RadicalsOxidation-ReductionPhotochemical ProcessesPhotosensitizing AgentsCoenzymesFree RadicalsPhotosensitizing AgentsPyridoxal Phosphate

Identifiers

PMID42649284

DOI10.1038/s41586-026-10930-9

PMCPMC13538046

What OpenQuestion holds

Textmetadata

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.