Evidence map›Paper›PMID 42648959›Full record

ReviewTrends in microbiology2026

Shiny metal catalysts at the origin of metabolism.

William F Martin, Nadja K Hoffmann, Manon L Schlikker

Abstract readReview
In one paragraph

Review in Trends in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William F MartinInstitute of Molecular Evolution, University of Düsseldorf, 40225 Düsseldorf, Germany. Electronic address: bill@hhu.de.
Nadja K HoffmannInstitute of Molecular Evolution, University of Düsseldorf, 40225 Düsseldorf, Germany.
Manon L SchlikkerInstitute of Molecular Evolution, University of Düsseldorf, 40225 Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metabolism is the reaction network that converts inanimate matter into living cells. There is no life without it. The network of approximately 400 enzymatic reactions that synthesize amino acids, nucleosides, and cofactors from compounds in the environment is conserved across life. Before enzymes, how did metabolism arise? The subsurface chemical environment of Earth's crust reveals clues. Serpentinizing (H

Indexed as

acetyl–CoA pathwayautotrophic originshydrothermal ventsorigin of lifeprebiotic phosphorylationserpentinization

Identifiers

PMID42648959
PMCPMC7619600

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.