ArticleClinical practice and cases in emergency medicine2026
Cerebral Kounis Syndrome-A Rare Case Report of Cerebral Vasospasm Following Anaphylaxis.
Article in Clinical practice and cases in emergency medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
introductionKounis syndrome describes anaphylaxis-induced coronary vasospasm and is often misdiagnosed as acute coronary syndrome. We report a similar phenomenon of cerebral vasospasm following anaphylaxis, a rare and under-recognized mimic of stroke. CASE REPORT: A previously healthy 45-year-old gentleman developed sudden right-sided hemiparesis and dysarthria while working outdoors, accompanied by generalized pruritus, rash, presyncope, dyspnea, palpitation, and abdominal pain. He received prompt intramuscular epinephrine and other anti-inflammatory agents, resulting in rapid symptom resolution and complete recovery in the emergency department. Computed tomography of the brain and other studies were unremarkable. This case underscores a rare neurological manifestation of anaphylaxis.
conclusionCerebral vasospasm is an unusual sequela of anaphylaxis that may lead to a diagnostic dilemma. Prompt administration of epinephrine is crucial for recovery. This case highlights the association between hypersensitivity reactions and cerebrovascular events, emphasizing the need for early recognition and timely intervention.
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