Evidence map›Paper›PMID 42647611›Full record

ArticleScience advances2026

Beyond animal glue: Paleoproteomic analysis of paint binders and adhesives in ancient Egypt.

Clara Granzotto, Rebecca J Stacey, Meaghan Mackie, Kate Fulcher, Fabiana Di Gianvincenzo, Neal Spencer, Cecilie Brøns, Luise Ørsted Brandt, Mia Broné, Carl Heron and 1 more

Abstract read
In one paragraph

Article in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Clara GranzottoGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5-7, 1353 Copenhagen, Denmark.ORCID 0000-0002-7839-4316
Rebecca J StaceyDepartment of Scientific Research, The British Museum, Great Russell St, London WC1B 3DG, UK.ORCID 0000-0002-5074-6180
Meaghan MackieGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5-7, 1353 Copenhagen, Denmark.ORCID 0000-0003-0763-7592
Kate FulcherDepartment of Scientific Research, The British Museum, Great Russell St, London WC1B 3DG, UK.ORCID 0000-0001-5379-6936
Fabiana Di GianvincenzoGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5-7, 1353 Copenhagen, Denmark.ORCID 0000-0003-3304-0749
Neal SpencerDepartment of Ancient Egypt and Sudan, The British Museum, Great Russell St, London WC1B 3DG, UK.ORCID 0000-0002-3443-2341
Cecilie BrønsNy Carlsberg Glyptotek, Dantes Plads 7, 1556 Copenhagen, Denmark.ORCID 0000-0001-7089-7958
Luise Ørsted BrandtGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5-7, 1353 Copenhagen, Denmark.ORCID 0000-0002-9777-0356
Mia BronéStatensmuseerförvärldskultur/National Museums of World Culture, Box 5306, 402 27 Göteborg, Sweden.ORCID 0009-0003-2413-2972
Carl HeronDepartment of Scientific Research, The British Museum, Great Russell St, London WC1B 3DG, UK.ORCID 0000-0002-5206-7464
Enrico CappelliniGlobe Institute, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5-7, 1353 Copenhagen, Denmark.ORCID 0000-0001-7885-7811

Funding

Wellcome Trust
6 · The paper itself

Abstract

Despite the wealth of artworks from ancient Egypt in collections worldwide, the number of analytical studies on the organic media used in paints and adhesives is limited, especially because microsamples are often required. In this study, we used mass spectrometry-based proteomics to confidently identify the species and tissues of origin of proteinaceous materials in painted ancient Egyptian artifacts from several collections dating 1425 BCE to 400 CE. Proteomics confirmed the use of glue prepared from the collagen of multiple animals and revealed the presence of plant proteins, including sesame and moringa products, previously undocumented in ancient Egyptian artworks. This prompts additional discussions about the origins of these materials, their symbolic and religious meaning in connection with deities, and their value within the artistic, cultural, and economic contexts of ancient Egypt. Our study demonstrates that combining paleoproteomics results with other analytical methods, archaeological evidence, and textual sources sheds light on expected and more unconventional organic materials in painted artworks from ancient Egypt.

Indexed as

AdhesivesPaintProteomicsAnimalsArchaeologyEgyptEgypt, AncientMass SpectrometryPlant ProteinsAdhesivesPlant Proteins

Identifiers

PMID42647611
PMCPMC13510678

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.