Evidence map›Paper›PMID 42647467›Full record

ArticlePLoS biology2026

How do anthropogenic changes affect wildlife microbiomes?

Katherine M Lagerstrom, Andrew P Dobson, Shane Campbell-Staton, Andrew H Moeller

Abstract read
In one paragraph

Article in PLoS biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katherine M LagerstromDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.ORCID https://orcid.org/0000-0002-8747-0544
Andrew P DobsonDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.
Shane Campbell-StatonDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.
Andrew H MoellerDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.

Funding

Uncovering the modes and genetics of gut bacterial transmissionR35GM138284 · NIGMS · PRINCETON UNIVERSITY · PI Andrew Moeller · 2020 to 2026
$2.4M
The genomics and consequences of gut bacterial adaptation to high-fat dietsR01DK139214 · NIDDK · PRINCETON UNIVERSITY · PI Andrew Moeller · 2024 to 2026
$1.3M
NIDDK NIH HHS R01 DK139214NIGMS NIH HHS R35 GM138284
6 · The paper itself

Abstract

Human activities are transforming ecosystems, but their effects on wildlife microbiota remain poorly understood. Pollution, habitat transformation, and altered host contact networks can reshape host-associated microbiota in context-dependent ways, including through symbiont loss, selection for antimicrobial resistance, shifts toward human-associated community states, and increased among-host variability. Whether these changes are transient or persistent, harmful or adaptive, or consequential for wildlife health and disease risk is largely unknown. This Unsolved Mystery highlights key mechanistic gaps and outlines future research strategies for the field, including studies that distinguish environmental filtering, dispersal limitation, host physiological responses, and cross-species microbial transmission.

Indexed as

Animals, WildAnthropogenic EffectsMicrobiotaAnimalsEcosystemHumansSymbiosis

Identifiers

PMID42647467
PMCPMC13514009

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.